PHF12 and ATP6V0D2

Data Source:
BioGRID (two hybrid)

		PHF12	ATP6V0D2
Description		PHD finger protein 12	ATPase H+ transporting V0 subunit d2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Sin3 Complex Transcription Repressor Complex Sin3-type Complex	Lysosomal Membrane Early Endosome Endosome Membrane Membrane Apical Plasma Membrane Vacuolar Proton-transporting V-type ATPase Complex Phagocytic Vesicle Membrane Proton-transporting V-type ATPase, V0 Domain Plasma Membrane Proton-transporting V-type ATPase Complex Extracellular Exosome
	Molecular Function	Transcription Corepressor Binding Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Phosphatidylinositol Binding Metal Ion Binding	Protein Binding Proton-transporting ATPase Activity, Rotational Mechanism
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated	Vacuolar Transport Vacuolar Acidification Insulin Receptor Signaling Pathway Regulation Of Macroautophagy Transferrin Transport Ion Transmembrane Transport Phagosome Acidification Proton Transmembrane Transport
Pathways			ROS and RNS production in phagocytes Insulin receptor recycling Transferrin endocytosis and recycling Amino acids regulate mTORC1 Ion channel transport
Drugs			Tiludronic acid
Diseases
GWAS			Adverse response to lamotrigine and phenytoin ( 22379998) Neutrophil count ( 32888494)
Interacting Genes		6 interacting genes: ATP6V0D2 BRCA1 H3-4 HDAC1 MORF4L1 SIN3A	20 interacting genes: ADRM1 AGO3 ARID5A CENPP CRX IKZF3 INCA1 MEOX2 NDUFB8 NICN1 PAX6 PHF12 POMC RBM15B REL RIBC1 RPS3 RUSC1 SEPTIN2 ZNF474
Entrez ID		57649	245972
HPRD ID		15123	16522
Ensembl ID		ENSG00000109118	ENSG00000147614
Uniprot IDs		C9J9G2 Q96QT6	A0A024R991 Q8N8Y2
PDB IDs		2L9S 2LKM
Enriched GO Terms of Interacting Partners?
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