PTGFR and PHOX2B

Data Source:
BioGRID (fluorescent resonance energy transfer)

		PTGFR	PHOX2B
Description		prostaglandin F receptor	paired like homeobox 2B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane	Chromatin Nucleoplasm
	Molecular Function	Prostaglandin F Receptor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Nervous System Process Noradrenergic Neuron Differentiation Noradrenergic Neuron Development Brainstem Development Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Population Proliferation Glial Cell Differentiation Regulation Of Gene Expression Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cell Differentiation In Hindbrain Medullary Reticular Formation Development Hindbrain Tangential Cell Migration Skeletal Muscle Cell Differentiation Negative Regulation Of Neuron Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription By RNA Polymerase II Autonomic Nervous System Development Enteric Nervous System Development Sympathetic Nervous System Development Parasympathetic Nervous System Development Inner Ear Development Efferent Axon Development In A Lateral Line Nerve Respiratory System Development Retrotrapezoid Nucleus Neuron Differentiation Sympathetic Ganglion Development Negative Regulation Of Cell Cycle Arrest Dopaminergic Neuron Differentiation Cellular Response To BMP Stimulus Positive Regulation Of Cold-induced Thermogenesis Neural Crest Cell Migration Involved In Autonomic Nervous System Development
Pathways		Prostanoid ligand receptors G alpha (q) signalling events
Drugs		Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod
Diseases			Congenital central hypoventilation syndrome (CCHS)
GWAS		Bipolar disorder ( 22182935) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)	Bone mineral density (femoral neck) ( 26911590) Hirschsprung disease ( 27702942)
Interacting Genes		5 interacting genes: AGTR1 PTGDS PTGER1 PTGER2 PTGES2
Entrez ID		5737	8929
HPRD ID		08988	09157
Ensembl ID		ENSG00000122420	ENSG00000109132
Uniprot IDs		P43088	Q99453
PDB IDs
Enriched GO Terms of Interacting Partners?
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