PTGFR and GTPBP4

Data Source:
BioGRID (biochemical)

		PTGFR	GTPBP4
Description		prostaglandin F receptor	GTP binding protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Prostaglandin F Receptor Activity	RNA Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Parturition Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression Response To Estradiol Response To Lipopolysaccharide Calcium-mediated Signaling Using Intracellular Calcium Source Negative Regulation Of Apoptotic Process Cellular Response To Prostaglandin D Stimulus	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Osteoblast Differentiation Negative Regulation Of DNA Replication Negative Regulation Of Cell Population Proliferation Negative Regulation Of Cell-cell Adhesion Negative Regulation Of Cell Migration Negative Regulation Of Protein Ubiquitination Negative Regulation Of Collagen Binding Protein Stabilization
Pathways		Prostanoid ligand receptors G alpha (q) signalling events
Drugs		Travoprost Latanoprost Bimatoprost Dinoprost tromethamine Tafluprost Latanoprostene bunod
Diseases
GWAS		Bipolar disorder ( 22182935) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Lung function in never smokers (high FEV1 vs average FEV1) ( 26423011) Skin fluorescence in type 1 diabetes ( 27207532) Systolic blood pressure (alcohol consumption interaction) ( 24376456)	Height ( 28552196)
Interacting Genes		5 interacting genes: AGTR1 PTGDS PTGER1 PTGER2 PTGES2	3 interacting genes: COPB1 SRPK2 YWHAG
Entrez ID		5737	23560
HPRD ID		08988	09976
Ensembl ID		ENSG00000122420	ENSG00000107937
Uniprot IDs		P43088	D2CFK9 Q9BZE4
PDB IDs			6LSS 6LU8
Enriched GO Terms of Interacting Partners?
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