HMCES and ACAD9

Data Source:
BioGRID (affinity chromatography technology, proximity labelling technology)

		HMCES	ACAD9
Description		5-hydroxymethylcytosine binding, ES cell specific	acyl-CoA dehydrogenase family member 9
Image			No pdb structure
GO Annotations	Cellular Component	Replication Fork	Nucleus Mitochondrion Mitochondrial Inner Membrane Dendrite Mitochondrial Membrane
	Molecular Function	Single-stranded DNA Binding DNA-(apurinic Or Apyrimidinic Site) Endonuclease Activity Protein Binding Peptidase Activity	Fatty-acyl-CoA Binding Long-chain-acyl-CoA Dehydrogenase Activity Protein Binding Very-long-chain-acyl-CoA Dehydrogenase Activity Flavin Adenine Dinucleotide Binding Medium-chain-acyl-CoA Dehydrogenase Activity
	Biological Process	Proteolysis Cellular Response To DNA Damage Stimulus Protein-DNA Covalent Cross-linking Positive Regulation Of Isotype Switching Double-strand Break Repair Via Alternative Nonhomologous End Joining	Long-chain Fatty Acid Metabolic Process Mitochondrial Respiratory Chain Complex I Assembly Medium-chain Fatty Acid Metabolic Process
Pathways			Complex I biogenesis
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Dental caries ( 23064961) Facial morphology traits (63 three-dimensional facial segments) ( 29459680)
Interacting Genes		3 interacting genes: APP FBXO25 NEDD4
Entrez ID		56941	28976
HPRD ID		13119	12412
Ensembl ID		ENSG00000183624	ENSG00000177646
Uniprot IDs		Q96FZ2	Q9H845
PDB IDs		5KO9 6OE7 6OEA 6OEB 6OOV
Enriched GO Terms of Interacting Partners?
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