CYP26B1 and CEBPG

Data Source:
BioGRID (affinity chromatography technology)

		CYP26B1	CEBPG
Description		cytochrome P450 family 26 subfamily B member 1	CCAAT enhancer binding protein gamma
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane	Chromatin Nucleus Nucleoplasm
	Molecular Function	Retinoic Acid Binding Monooxygenase Activity Iron Ion Binding Protein Binding Retinoic Acid 4-hydroxylase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, NAD(P)H As One Donor, And Incorporation Of One Atom Of Oxygen Heme Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Transcription Factor Binding Identical Protein Binding Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding, Bending Protein-containing Complex Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Cell Fate Determination Establishment Of T Cell Polarity Kidney Development Vitamin Metabolic Process Xenobiotic Metabolic Process Inflammatory Response Male Meiotic Nuclear Division Spermatogenesis Proximal/distal Pattern Formation Positive Regulation Of Gene Expression Sterol Metabolic Process Embryonic Limb Morphogenesis Response To Vitamin A Retinoic Acid Catabolic Process Retinoic Acid Metabolic Process Tongue Morphogenesis Regulation Of T Cell Differentiation Retinoic Acid Receptor Signaling Pathway Negative Regulation Of Retinoic Acid Receptor Signaling Pathway Bone Morphogenesis Establishment Of Skin Barrier Cornification Cellular Response To Retinoic Acid Positive Regulation Of Tongue Muscle Cell Differentiation	Liver Development Regulation Of Transcription By RNA Polymerase II Immune Response MRNA Metabolic Process B Cell Differentiation Positive Regulation Of Interferon-gamma Production Natural Killer Cell Mediated Cytotoxicity Enucleate Erythrocyte Differentiation Positive Regulation Of DNA Binding Negative Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of DNA Repair Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of DNA-binding Transcription Factor Activity
Pathways		Vitamins RA biosynthesis pathway Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA)	ATF4 activates genes in response to endoplasmic reticulum stress Response of EIF2AK4 (GCN2) to amino acid deficiency Response of EIF2AK1 (HRI) to heme deficiency
Drugs		Tretinoin
Diseases
GWAS		Cardiovascular death or myocardial infarction in response to clopidogrel treatment ( 32472697) Heel bone mineral density ( 30598549) Height ( 31562340) IgA levels ( 28628107) Malaria ( 31844061) Schizophrenia ( 25056061)	Inflammatory bowel disease ( 23128233) Schizophrenia ( 26198764)
Interacting Genes		1 interacting genes: NEDD4L	23 interacting genes: ATF2 ATF3 ATF4 ATF5 BATF BATF2 BATF3 CEBPA CEBPB CEBPD CEBPE CREB3 CREB3L3 DBP DDIT3 FOS FOSL1 GTF2F2 JUN MLLT6 PFDN6 PLAU POLR2M
Entrez ID		56603	1054
HPRD ID		05550	00738
Ensembl ID		ENSG00000003137	ENSG00000153879
Uniprot IDs		E7ER08 Q9NR63	P53567
PDB IDs
Enriched GO Terms of Interacting Partners?
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