KLK7 and FUZ

Data Source:
BioGRID (affinity chromatography technology)

		KLK7	FUZ
Description		kallikrein related peptidase 7	fuzzy planar cell polarity protein
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Secretory Granule Epidermal Lamellar Body	Cytoplasm Cytoskeleton Cell Projection Extracellular Exosome
	Molecular Function	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity	Protein Binding
	Biological Process	Positive Regulation Of Antibacterial Peptide Production Proteolysis Epidermis Development Extracellular Matrix Disassembly	Establishment Of Planar Polarity Neural Tube Closure Hair Follicle Development Negative Regulation Of Cell Population Proliferation Regulation Of Smoothened Signaling Pathway Embryonic Body Morphogenesis Protein Transport Vesicle-mediated Transport Negative Regulation Of Cell Migration Positive Regulation Of Cilium Assembly Embryonic Skeletal System Morphogenesis Cilium Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Neural Crest Formation Non-motile Cilium Assembly Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation
Pathways		Degradation of the extracellular matrix	Hedgehog 'off' state
Drugs		L-alanyl-N-[(1S,2R)-1-benzyl-2-hydroxypropyl]-L-alaninamide
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269)
Interacting Genes		10 interacting genes: APP BAG4 CCND1 CDSN CHEK2 PTPN1 PTPRJ STK11 TGFB1 WT1	1 interacting genes: CPLANE2
Entrez ID		5650	80199
HPRD ID		05115	08662
Ensembl ID		ENSG00000169035	ENSG00000010361
Uniprot IDs		A0A024R4H6 B4DHX9 P49862	A0A024QZF7 Q9BT04
PDB IDs		2QXG 2QXH 2QXI 2QXJ 3BSQ 5FAH 5Y9L 5YJK 6SHH 6SHI 6SJU 6Y4S
Enriched GO Terms of Interacting Partners?
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