EIF4ENIF1 and NIN

Data Source:
BioGRID (genetic interference)

		EIF4ENIF1	NIN
Description		eukaryotic translation initiation factor 4E nuclear import factor 1	ninein
Image			No pdb structure
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Cytosol Membrane PML Body Nuclear Speck Intracellular Membrane-bounded Organelle	Pericentriolar Material Spindle Pole Nucleoplasm Nucleolus Centrosome Centriole Cytoplasmic Microtubule Plasma Membrane Dendrite Axonal Growth Cone Apical Part Of Cell Mitotic Spindle Mitotic Spindle Pole Ciliary Transition Fiber Centriolar Subdistal Appendage
	Molecular Function	RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding Kinase Binding	Calcium Ion Binding Protein Binding GTP Binding Kinase Binding Microtubule Minus-end Binding
	Biological Process	Protein Import Into Nucleus Negative Regulation Of Translation Stem Cell Population Maintenance Gene Silencing By RNA P-body Assembly Negative Regulation Of Neuron Differentiation MRNA Stabilization Nuclear Export Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Positive Regulation Of MiRNA Mediated Inhibition Of Translation	Protein Localization Centriole-centriole Cohesion Corpus Callosum Morphogenesis Corticospinal Tract Morphogenesis Positive Regulation Of Microtubule Polymerization Microtubule Anchoring At Centrosome Collateral Sprouting Positive Regulation Of Axonogenesis Centrosome Localization Centrosome-templated Microtubule Nucleation
Pathways
Drugs
Diseases
GWAS		Age-related hearing impairment ( 24939585) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663)	Asthma (time to childhood onset) x early life tobacco smoke interaction ( 31379025) Cognitive performance ( 20125193) Diastolic blood pressure ( 30578418) Lupus nephritis in systemic lupus erythematosus ( 24925725) Mean platelet volume ( 27863252) Periodontal disease-related phenotype (Socransky) ( 24347629) Pulse pressure ( 30578418) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		27 interacting genes: ATXN1 CDK6 CFAP206 DEF6 DTX2 EFHC1 EIF3E EIF4E EIF4E2 FANCL FDPS HNRNPF KRT19 L3MBTL2 MGAT5B OIP5 PRR20A PRR20B PRR20C PRR20D PRR20E SMAD3 SPAG5 TCHP TTC19 TXLNA USP2	14 interacting genes: ABI1 AUNIP AURKA BICD1 GSK3B GTSE1 KLC1 PIAS1 PRKACA RBM10 RTRAF SUMO1 UBE2I YWHAE
Entrez ID		56478	51199
HPRD ID		10456	09785
Ensembl ID		ENSG00000184708	ENSG00000100503
Uniprot IDs		A0A024R1K0 Q9NRA8	Q5XUU0 Q8N4C6
PDB IDs		5ANR 6F9W 6X2R
Enriched GO Terms of Interacting Partners?
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