PRRG2 and CYTH2

Data Source:
BioGRID (affinity chromatography technology)

		PRRG2	CYTH2
Description		proline rich and Gla domain 2	cytohesin 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane	Golgi Membrane Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Growth Cone
	Molecular Function	Calcium Ion Binding Protein Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process		Endocytosis Actin Cytoskeleton Organization Regulation Of ARF Protein Signal Transduction Regulation Of Catalytic Activity
Pathways			Intra-Golgi traffic
Drugs			Inositol 1,3,4,5-Tetrakisphosphate Formic acid 1D-myo-inositol 1,4,5-trisphosphate S,S-(2-Hydroxyethyl)Thiocysteine Brefeldin A
Diseases
GWAS		Hematocrit ( 32888494 27863252) Hemoglobin ( 32888494) Hemoglobin levels ( 32327693) Red blood cell count ( 32888494 27863252) Schizophrenia ( 25056061 29483656 30285260)	Abstraction and mental flexibility ( 31596458)
Interacting Genes		6 interacting genes: CRK FAM221A FATE1 NEDD4 SGTA YAP1	31 interacting genes: ADORA2A ALDOA APC ARF1 ARF6 ARFGAP1 ARL4A ARL4D ARRB1 ARRB2 ATP6V0A1 ATP6V0A2 ATP6V0A4 CCDC120 CNKSR1 CUX1 CYTIP DOCK1 GGA3 GNAQ INAVA IPCEF1 ITGB2 MAPK6 PIK3CA PNPLA2 PRKCA PRKCB PRKCG TCIRG1 TRIM23
Entrez ID		5639	9266
HPRD ID		09189	03925
Ensembl ID		ENSG00000126460	ENSG00000105443
Uniprot IDs		O14669	Q99418
PDB IDs			1PBV 1R8M 1R8Q 1R8S 1S9D 4JMI 4JMO 4JWL 4JXH 4L5M 4Z21
Enriched GO Terms of Interacting Partners?
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