NGLY1 and LIMD1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, far western blotting)

		NGLY1	LIMD1
Description		N-glycanase 1	LIM domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	P-body Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Plasma Membrane Adherens Junction Focal Adhesion RISC Complex
	Molecular Function	Peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine Amidase Activity Protein Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Protein Folding Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Glycoprotein Catabolic Process Protein Deglycosylation	Response To Hypoxia Osteoblast Development Regulation Of Transcription, DNA-templated Cytoskeleton Organization Regulation Of Cell Shape Phosphorylation Cell Migration P-body Assembly Gene Silencing By MiRNA Negative Regulation Of Hippo Signaling Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Silencing By MiRNA
Pathways		N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Drugs
Diseases
GWAS			Acne (severe) ( 24927181) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 30578418)
Interacting Genes		18 interacting genes: APP BICRAL FAF1 GUCD1 NPAS2 NSFL1C PAX5 PAX6 RAD23A RAD23B SRPK2 TCF12 TRAFD1 TRIM54 UBQLN1 UBXN2B VCP VMAC	6 interacting genes: APP BRCA2 HIPK3 RPP14 STAC TRAF6
Entrez ID		55768	8994
HPRD ID		10118	05177
Ensembl ID		ENSG00000151092	ENSG00000144791
Uniprot IDs		Q96IV0	Q9UGP4
PDB IDs		2CCQ 2CM0
Enriched GO Terms of Interacting Partners?
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