EXOC1 and SFR1

Data Source:
BioGRID (two hybrid)

		EXOC1	SFR1
Description		exocyst complex component 1	SWI5 dependent homologous recombination repair protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Flemming Body Cytoplasmic Side Of Apical Plasma Membrane	Nucleus Swi5-Sfr1 Complex
	Molecular Function	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding	Protein Binding Nuclear Receptor Coactivator Activity
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Protein Transport Viral Process Regulation Of Macroautophagy Phosphatidylinositol-mediated Signaling Positive Regulation Of Protein Secretion Defense Response To Virus	Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Transcription, DNA-templated Cellular Response To Estrogen Stimulus
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Cerebrospinal P-tau181p levels ( 28247064) Cervical cancer ( 23817570) Daytime sleep phenotypes ( 27126917) Urinary albumin excretion ( 32277301) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		30 interacting genes: ATG14 CCDC88A CCDC93 CCHCR1 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST KANSL1 KDM1A LUC7L2 MACF1 MTNR1A NUF2 NUP54 RALA RB1CC1 RESF1 RUBCN SFR1 SH3BP5 SNAPIN SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO	15 interacting genes: CDC5L CEP70 DTNBP1 EXOC1 FBXO7 HMBOX1 MRFAP1L1 NDC80 NMI RAD51 RINT1 RNF40 SWI5 TFIP11 TRAF3IP1
Entrez ID		55763	119392
HPRD ID		07615	12590
Ensembl ID		ENSG00000090989	ENSG00000156384
Uniprot IDs		A0A024RDA1 A1LT29 Q9NV70	Q86XK3
PDB IDs
Enriched GO Terms of Interacting Partners?
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