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THAP1 and PID1
Data Source:
BioGRID
(two hybrid)
THAP1
PID1
Description
THAP domain containing 1
phosphotyrosine interaction domain containing 1
Image
No pdb structure
GO Annotations
Cellular Component
Chromatin
Fibrillar Center
Nucleus
Nucleoplasm
PML Body
Intracellular Membrane-bounded Organelle
Cytoplasm
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Activity
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Endothelial Cell Proliferation
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Cell Cycle
Regulation Of Mitotic Cell Cycle
Negative Regulation Of Protein Phosphorylation
Energy Reserve Metabolic Process
Positive Regulation Of Gene Expression
Regulation Of Mitochondrial Fusion
Cellular Response To Leptin Stimulus
Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Glucose Import
Negative Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Mitochondrial Membrane Potential
Positive Regulation Of Fat Cell Proliferation
Mitochondrion Morphogenesis
Cellular Response To Cytokine Stimulus
Cellular Response To Interleukin-6
Cellular Response To Tumor Necrosis Factor
Cellular Response To Fatty Acid
Negative Regulation Of Protein Localization To Plasma Membrane
Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Reactive Oxygen Species Metabolic Process
Negative Regulation Of ATP Biosynthetic Process
Positive Regulation Of ATP Biosynthetic Process
Pathways
Drugs
Diseases
Primary torsion dystonia (PTD)
GWAS
Pelvic organ prolapse (moderate/severe) (
26545240
)
Chronic obstructive pulmonary disease (
28166215
30804561
)
Coronary artery disease (
33020668
)
FEV1 (
30804560
)
HDL cholesterol levels (
32203549
)
Lung function (FEV1/FVC) (
28166213
30804560
)
Medication use (antimigraine preparations) (
31015401
)
Peak expiratory flow (
30804560
)
Pulmonary function (smoking interaction) (
23284291
)
Response to antipsychotic treatment in schizophrenia (reasoning) (
21107309
)
Total cholesterol levels (
30498476
)
Triglyceride levels (
32203549
)
Urinary albumin excretion (
30220432
)
Urinary albumin excretion (no hypertensive medication) (
30220432
)
Interacting Genes
105 interacting genes:
ABCF3
ACOT7
AEBP2
AKAP17A
AKAP9
AP2B1
APP
ARL6IP4
BAG5
BEND7
BMS1P1
BYSL
C1orf216
C1orf35
C4orf45
C7orf50
CDC37
CDKN2D
CHD2
CSNK2A1
DCAF8
DVL2
EEF1AKNMT
FAM124A
FAM133A
FAM9A
FGF10
FGF11
FGF12
FXR2
GAS8
GPATCH2L
HNRNPLL
HYPK
INO80B
KANK2
KLF12
KRTAP10-7
L3MBTL2
LASP1
LMNB2
LMO3
LNX1
MFAP1
MIS18A
MORF4L1
MORF4L2
MRPL11
MRPL53
NDUFAB1
NKAP
NKAPD1
NTAQ1
NUP62
PAWR
PHF1
PHF19
PID1
PNKP
POLR2L
POLR2M
POU6F2
PPIG
PRKAA1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QKI
RAD54L2
RALY
RALYL
RBM10
RBM39
RIPPLY1
RNF4
RP9P
RPL22
RPS25
SAP30BP
SERF2
SLU7
SPANXN2
SREK1IP1
STRBP
TCEA2
TCEANC
TPM3
TRAF5
TRIM26
TRIP10
TTLL10
TXN2
U2AF2
UBE2I
VCX2
WT1
YES1
ZBTB48
ZCCHC10
ZGPAT
ZNF385C
ZNF408
ZNF526
15 interacting genes:
ADAMTSL4
BANP
CBY2
CCDC33
CPSF7
CRX
DNAAF6
GOLGA2
GOPC
KRTAP10-1
LRP1
MDFI
NME1
NOTCH2NLA
THAP1
Entrez ID
55145
55022
HPRD ID
15496
07944
Ensembl ID
ENSG00000131931
ENSG00000153823
Uniprot IDs
Q9NVV9
Q7Z2X4
PDB IDs
2JTG
2KO0
2L1G
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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