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HPF1 and H1-0
Data Source:
BioGRID
(pull down)
HPF1
H1-0
Description
histone PARylation factor 1
H1.0 linker histone
Image
GO Annotations
Cellular Component
Nucleus
Chromatin
Nucleosome
Euchromatin
Nucleus
Nucleoplasm
Golgi Apparatus
Actin Cytoskeleton
Nuclear Body
Transcription Repressor Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Histone Binding
Poly-ADP-D-ribose Binding
Minor Groove Of Adenine-thymine-rich DNA Binding
Double-stranded DNA Binding
RNA Binding
Protein Binding
Chromatin DNA Binding
Nucleosomal DNA Binding
Biological Process
Cellular Response To DNA Damage Stimulus
Regulation Of Protein ADP-ribosylation
Peptidyl-serine ADP-ribosylation
Negative Regulation Of Transcription By RNA Polymerase II
Apoptotic DNA Fragmentation
Nucleosome Assembly
Chromatin Silencing
Nucleosome Positioning
Chromosome Condensation
Negative Regulation Of Chromatin Silencing
Negative Regulation Of DNA Recombination
Positive Regulation Of Transcription Regulatory Region DNA Binding
Pathways
Apoptosis induced DNA fragmentation
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Interacting Genes
15 interacting genes:
EIF6
FBXO7
H1-0
H1-5
H2BC4
H3-3A
H3-4
H3C1
HMGA1
HMGB1
HMGN1
HMGN2
HMGN4
PARP1
PARP2
21 interacting genes:
APP
CCNE1
CDK1
CDK2
CDK4
CDK5
FBXO7
GRB2
HPF1
IKBKG
IPO5
IPO7
KPNA2
KPNB1
NEDD4L
NOA1
PARP1
PARP2
PRKCB
RAD51B
XBP1
Entrez ID
54969
3005
HPRD ID
07924
00819
Ensembl ID
ENSG00000056050
ENSG00000189060
Uniprot IDs
Q9NWY4
P07305
PDB IDs
6TX2
6TX3
6X0L
6X0M
6X0N
6HQ1
6LA8
6LA9
6N88
6N89
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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