BCOR and CPNE2

Data Source:
HPRD (two hybrid)

		BCOR	CPNE2
Description		BCL6 corepressor	copine 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm BCOR Complex	Nucleus Cytoplasm Plasma Membrane Extracellular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Heat Shock Protein Binding Histone Deacetylase Binding	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Histone H3-K36 Methylation Blastocyst Hatching Heart Development Negative Regulation Of Bone Mineralization Histone H2A Monoubiquitination Odontogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Histone H3-K4 Methylation Roof Of Mouth Development Specification Of Axis Polarity Negative Regulation Of Tooth Mineralization	Cellular Response To Calcium Ion
Pathways
Drugs
Diseases		Anophthalmia and microphthalmia (A/M)
GWAS		Pit-and-Fissure caries ( 23470693) Platelet count ( 29403010) Refractive error ( 32231278) Venous thromboembolism ( 31676865)
Interacting Genes		17 interacting genes: BCL6 CPNE1 CPNE2 CPNE4 HDAC1 HDAC3 HDAC4 HDAC5 HDAC6 MLLT3 NAA10 NACC1 PCGF1 PCGF3 SP1 UBTD1 USP7	28 interacting genes: ACTB ANXA7 BCOR CDKN1A CT55 EFHC2 GBP7 IKBKG KATNBL1 LNX1 MEI4 MEOX2 MYCBP NCKIPSD PDCD6 PICK1 PPP5C RDX REL SKIL SORBS3 TCF4 TERF2IP THAP4 TRIM27 UBA3 UBE2M UBE2O
Entrez ID		54880	221184
HPRD ID		06458	05015
Ensembl ID		ENSG00000183337	ENSG00000140848
Uniprot IDs		Q6W2J9	Q96FN4
PDB IDs		2N1L 3BIM 4HPL 6B7G
Enriched GO Terms of Interacting Partners?
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