PLOD2 and LYPLA1

Data Source:
BioGRID (affinity chromatography technology)

		PLOD2	LYPLA1
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 2	lysophospholipase 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Membrane Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane Nuclear Membrane Extracellular Exosome
	Molecular Function	Iron Ion Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity	Phospholipase Activity Lysophospholipase Activity Protein Binding Palmitoyl-(protein) Hydrolase Activity Lipase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Response To Hypoxia Cellular Protein Modification Process Protein O-linked Glycosylation Peptidyl-lysine Hydroxylation Protein Phosphopantetheinylation Hydroxylysine Biosynthetic Process	Protein Depalmitoylation Fatty Acid Metabolic Process Protein Phosphopantetheinylation Negative Regulation Of Golgi To Plasma Membrane Protein Transport Regulation Of Nitric-oxide Synthase Activity
Pathways		Collagen biosynthesis and modifying enzymes	eNOS activation RAS processing
Drugs		Ascorbic acid
Diseases		Bruck syndrome
GWAS		Height ( 31562340) Obesity-related traits ( 23251661) Squamous cell lung carcinoma ( 28604730) Zinc levels ( 26025379)	Itch intensity from mosquito bite adjusted by bite size ( 28199695) Pelvic organ prolapse (moderate/severe) ( 26545240) Urinary albumin-to-creatinine ratio ( 26631737) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625)
Interacting Genes		1 interacting genes: LINC01554	3 interacting genes: ANXA2 GOLGA2 SFMBT2
Entrez ID		5352	10434
HPRD ID		03519	07063
Ensembl ID		ENSG00000152952	ENSG00000120992
Uniprot IDs		O00469	A0A087X1K9 B4DP64 O75608 Q6IAQ1
PDB IDs			1FJ2 5SYM 6QGN 6QGO 6QGQ 6QGS
Enriched GO Terms of Interacting Partners?
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