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LSM7 and ARF6
Data Source:
BioGRID
(affinity chromatography technology)
LSM7
ARF6
Description
LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated
ADP ribosylation factor 6
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
U6 SnRNP
U12-type Spliceosomal Complex
Cytosol
U4/U6 X U5 Tri-snRNP Complex
U2-type Prespliceosome
U2-type Precatalytic Spliceosome
Catalytic Step 2 Spliceosome
Spliceosomal Tri-snRNP Complex
Lsm2-8 Complex
Lsm1-7-Pat1 Complex
Ribonucleoprotein Complex
Ruffle
Cytoplasm
Endosome
Golgi Apparatus
Cytosol
Plasma Membrane
Focal Adhesion
Cell Cortex
Membrane
Endocytic Vesicle
Filopodium Membrane
Early Endosome Membrane
Cleavage Furrow
Recycling Endosome Membrane
Extracellular Exosome
Flemming Body
Presynapse
Glutamatergic Synapse
Molecular Function
RNA Binding
Protein Binding
U6 SnRNA Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
Thioesterase Binding
Protein N-terminus Binding
Biological Process
MRNA Splicing, Via Spliceosome
Exonucleolytic Catabolism Of Deadenylated MRNA
Liver Development
Intracellular Protein Transport
Cell Cycle
Cell Adhesion
Nervous System Development
Vesicle-mediated Transport
Cell Differentiation
Positive Regulation Of Actin Filament Polymerization
Cortical Actin Cytoskeleton Organization
Endocytic Recycling
Myeloid Cell Apoptotic Process
Protein Localization To Cell Surface
Regulation Of Rac Protein Signal Transduction
Protein Localization To Endosome
Negative Regulation Of Receptor-mediated Endocytosis
Synaptic Vesicle Endocytosis
Positive Regulation Of Protein Secretion
Cell Division
Regulation Of Filopodium Assembly
Positive Regulation Of Keratinocyte Migration
Regulation Of Dendritic Spine Development
Establishment Of Epithelial Cell Polarity
Ruffle Assembly
Hepatocyte Apoptotic Process
Maintenance Of Postsynaptic Density Structure
Positive Regulation Of Focal Adhesion Disassembly
Positive Regulation Of Protein Localization To Plasma Membrane
Regulation Of Presynapse Assembly
Cellular Response To Nerve Growth Factor Stimulus
Negative Regulation Of Protein Localization To Cell Surface
Negative Regulation Of Dendrite Development
Pathways
mRNA decay by 5' to 3' exoribonuclease
mRNA decay by 5' to 3' exoribonuclease
mRNA Splicing - Major Pathway
TBC/RABGAPs
Clathrin-mediated endocytosis
MET receptor recycling
Drugs
5'-Guanosine-Diphosphate-Monothiophosphate
Guanosine-5'-Diphosphate
Myristic acid
Diseases
GWAS
Parkinson's disease (
28892059
)
Erythema nodosum in inflammatory bowel disease (
24487271
)
Interacting Genes
25 interacting genes:
DDIT4L
EPHA2
EXOSC6
EXOSC8
LDB1
LSM1
LSM2
LSM3
LSM4
LSM5
LSM6
LSM8
MYH13
NPY1R
PFKM
RAB29
RASSF5
SART3
SMN1
SNRPD3
SNRPF
SYT17
TACC1
TCL1B
ZSCAN26
37 interacting genes:
AGAP1
AP1B1
AP3B1
AP3D1
AP3S2
APBB1
APP
ARFIP2
ARHGAP10
ARRB1
ARRB2
ASAP1
ASAP2
ASAP3
ATP6V0C
CAPN1
CHRM3
CYTH1
CYTH2
EXOC5
EZR
HTR2A
IKBKG
ITSN1
MEOX2
MT2A
PALS1
PIP5K1A
PIP5K1C
PLD1
RAB11A
RAB11FIP3
RAB11FIP4
RAB11FIP5
SMAP1
SPAG9
ZNF709
Entrez ID
51690
382
HPRD ID
06287
02714
Ensembl ID
ENSG00000130332
ENSG00000165527
Uniprot IDs
Q9UK45
P62330
PDB IDs
3JCR
5O9Z
6AH0
6AHD
6QW6
6QX9
1E0S
2A5D
2A5F
2A5G
2BAO
2BAU
2J5X
2W83
3LVQ
3LVR
3N5C
3PCR
4FME
4KAX
6BBP
6BBQ
6PAU
Enriched GO Terms of Interacting Partners
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