ASB2 and TRIP11

Data Source:
BioGRID (affinity chromatography technology)

		ASB2	TRIP11
Description		ankyrin repeat and SOCS box containing 2	thyroid hormone receptor interactor 11
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Cytosol	Golgi Membrane Inner Acrosomal Membrane Outer Acrosomal Membrane Nucleoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Cytoskeleton Cilium Nuclear Speck Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Activity	Transcription Coactivator Activity Protein Binding Small GTPase Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Signal Transduction Protein Ubiquitination Intracellular Signal Transduction Skeletal Muscle Cell Differentiation Post-translational Protein Modification	Ventricular Septum Development Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Transcription By RNA Polymerase II Protein Glycosylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Intraciliary Transport Involved In Cilium Assembly Positive Regulation Of Transcription, DNA-templated Cartilage Development Inner Ear Receptor Cell Stereocilium Organization Golgi Ribbon Formation Vesicle Tethering To Golgi
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation	Intraflagellar transport Intra-Golgi traffic Signaling by FLT3 fusion proteins Signaling by FLT3 fusion proteins
Drugs
Diseases			Achodrogenesis type IA
GWAS		Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 26184070) Sum eosinophil basophil counts ( 27863252)	Body size at age 10 ( 32376654) FEV1 ( 30804560) HDL cholesterol levels x thiazide or thiazide-like diuretics use interaction ( 31806883) Height ( 28552196 20881960 25282103 25429064 31562340 18391950 18391951) LDL cholesterol levels x loop diuretics use interaction ( 31806883) Lung function (FEV1) ( 26635082) Lung function (FVC) ( 26635082 30804560) Refractive error ( 32231278) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes		6 interacting genes: ELOB FLNA FLNB SMAD9 UBC UBE2D1	6 interacting genes: ARNT ATXN1L MYBPC2 PSMC5 RB1 THRA
Entrez ID		51676	9321
HPRD ID		05768	05143
Ensembl ID		ENSG00000100628	ENSG00000100815
Uniprot IDs		A0A024R6E7 Q96Q27	Q15643
PDB IDs
Enriched GO Terms of Interacting Partners?
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