PDK4 and REEP5

Data Source:
BioGRID (biochemical)

		PDK4	REEP5
Description		pyruvate dehydrogenase kinase 4	receptor accessory protein 5
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Endoplasmic Reticulum Integral Component Of Membrane Endoplasmic Reticulum Tubular Network
	Molecular Function	Protein Kinase Activity Pyruvate Dehydrogenase (acetyl-transferring) Kinase Activity Protein Binding ATP Binding	Molecular_function Protein Binding
	Biological Process	Glucose Metabolic Process Protein Phosphorylation Regulation Of PH Insulin Receptor Signaling Pathway Cellular Response To Starvation Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Regulation Of Cellular Ketone Metabolic Process Regulation Of Glucose Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Glucose Homeostasis Response To Starvation Regulation Of Bone Resorption Regulation Of Fatty Acid Oxidation Cellular Response To Fatty Acid Reactive Oxygen Species Metabolic Process Negative Regulation Of Anoikis	Endoplasmic Reticulum Organization Biological_process Regulation Of Intracellular Transport
Pathways		Regulation of pyruvate dehydrogenase (PDH) complex Signaling by Retinoic Acid	Olfactory Signaling Pathway
Drugs		Tretinoin 4-[4-(4-methoxyphenyl)-5-methyl-1H-pyrazol-3-yl]benzene-1,3-diol
Diseases
GWAS		Refractive error ( 32231278)	Attention deficit hyperactivity disorder ( 18839057) Reaction time ( 29844566)
Interacting Genes		4 interacting genes: DLAT PDHA1 PLEKHF2 TRIM63	13 interacting genes: ABHD4 ARFGAP1 ARFIP2 CHRM5 GTF2H1 NUDT3 PBX3 PITPNC1 RAB5B RABAC1 RGS2 SNX1 VKORC1
Entrez ID		5166	7905
HPRD ID		03957	15918
Ensembl ID		ENSG00000004799	ENSG00000129625
Uniprot IDs		A4D1H4 Q16654	Q00765
PDB IDs		2E0A 2ZDX 2ZDY 2ZKJ 3D2R
Enriched GO Terms of Interacting Partners?
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