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NELFCD and ARPC4
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
NELFCD
ARPC4
Description
negative elongation factor complex member C/D
actin related protein 2/3 complex subunit 4
Image
GO Annotations
Cellular Component
Nucleoplasm
Membrane
NELF Complex
Nucleus
Cytosol
Arp2/3 Protein Complex
Site Of Double-strand Break
Cell Projection
Extracellular Exosome
Molecular Function
RNA Binding
Protein Binding
Structural Constituent Of Cytoskeleton
Protein Binding
Enzyme Binding
Protein-macromolecule Adaptor Activity
Actin Filament Binding
Biological Process
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
Negative Regulation Of Transcription Elongation From RNA Polymerase II Promoter
Positive Regulation Of Viral Transcription
Actin Filament Polymerization
Arp2/3 Complex-mediated Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Actin Nucleation
Ephrin Receptor Signaling Pathway
Membrane Organization
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA Polymerase II Transcription Elongation
Regulation of actin dynamics for phagocytic cup formation
Regulation of actin dynamics for phagocytic cup formation
EPHB-mediated forward signaling
RHO GTPases Activate WASPs and WAVEs
RHO GTPases Activate WASPs and WAVEs
Clathrin-mediated endocytosis
FCGR3A-mediated phagocytosis
FCGR3A-mediated phagocytosis
Drugs
N-[2-(2-methyl-1H-indol-3-yl)ethyl]thiophene-2-carboxamide
(2S)-2-(3-bromophenyl)-3-(5-chloro-2-hydroxyphenyl)-1,3-thiazolidin-4-one
Diseases
GWAS
Mean platelet volume (
32888494
27863252
)
Platelet distribution width (
27863252
)
Interacting Genes
21 interacting genes:
AAMP
AR
ARAF
ARPC4
CACNA1A
CDSN
DNAJA1
ENDOV
EPRS1
FRMD5
GSTM4
HDAC11
MTA1
NELFA
NELFB
PRMT5
SERF2
SMAD4
TXK
UBE3A
ZNF638
13 interacting genes:
ACTR2
ACTR3
ARPC1B
ARPC2
ARPC3
ARPC5
ARPC5L
CLK1
METTL21A
NELFCD
PNMA5
RNF130
WASL
Entrez ID
51497
10093
HPRD ID
16096
10368
Ensembl ID
ENSG00000101158
ENSG00000241553
Uniprot IDs
H0UI80
Q8IXH7
P59998
PDB IDs
5L3X
6GML
6UHC
6YW6
6YW7
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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