PHF21A and HMG20B

Data Source:
HPRD (in vitro)

		PHF21A	HMG20B
Description		PHD finger protein 21A	high mobility group 20B
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm DNA Repair Complex	Nucleus Nucleoplasm Chromosome Nuclear Body
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Metal Ion Binding	DNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Blood Coagulation	Chromatin Organization Cell Cycle Blood Coagulation Regulation Of Gene Expression Negative Regulation Of Protein Sumoylation Skeletal Muscle Cell Differentiation Positive Regulation Of Neuron Differentiation
Pathways		HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production	HDACs deacetylate histones Potential therapeutics for SARS Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Axial length ( 24144296) Height ( 29782485) Menarche (age at onset) ( 21102462 25231870) Refractive error ( 32231278) Triglyceride levels ( 32203549) Urate levels ( 31578528)
Interacting Genes		18 interacting genes: BANP EXOSC8 FHL2 FHL3 H3C14 HDAC1 HDAC2 HMG20A HMG20B KDM1A KRT40 L3MBTL3 LPXN NUP62 RCOR1 SP3 TRAF1 ZYX	28 interacting genes: APP BRCA2 C14orf119 CCDC102B CCDC136 CCDC85B E2F6 ERP29 FBXO7 HMG20A HNRNPL KIF4A KRT15 KRT38 MID1 NKX3-1 NUTF2 PHF21A PIAS2 PPP1R13B SNAPC5 SYCE1 TACC2 TFIP11 TRAF1 USHBP1 VIM WAC
Entrez ID		51317	10362
HPRD ID		10516	05703
Ensembl ID		ENSG00000135365	ENSG00000064961
Uniprot IDs		Q96BD5	Q9P0W2
PDB IDs		2PUY 2YQL
Enriched GO Terms of Interacting Partners?
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