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BFAR and UBE2W
Data Source:
BioGRID
(two hybrid)
BFAR
UBE2W
Description
bifunctional apoptosis regulator
ubiquitin conjugating enzyme E2 W
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Integral Component Of Plasma Membrane
Membrane
Integral Component Of Endoplasmic Reticulum Membrane
Nucleus
Nucleoplasm
Molecular Function
Protein Binding
Protein-macromolecule Adaptor Activity
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Caspase Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Protein Polyubiquitination
Ubiquitin-dependent Protein Catabolic Process
Apoptotic Process
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Negative Regulation Of IRE1-mediated Unfolded Protein Response
Protein Polyubiquitination
DNA Repair
Protein Monoubiquitination
Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins
Protein Ubiquitination
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein K11-linked Ubiquitination
Cellular Response To Misfolded Protein
Pathways
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Malaria (
31844061
)
Manganese levels (
26025379
)
Urate levels in obese individuals (
25811787
)
Interacting Genes
12 interacting genes:
BCL2
CASP10
CASP8
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2K
UBE2N
UBE2U
UBE2W
78 interacting genes:
AKR1C3
AMFR
BARD1
BFAR
BIRC2
BIRC8
BRCA1
CADPS2
CBL
CHFR
CNOT4
DNMT3B
DTX3
DTX3L
DZIP3
EED
FANCL
LRSAM1
MAP3K1
MAPT
MARCHF3
MARCHF5
MGRN1
MIB1
MID1
MKRN1
MKRN3
MUL1
PJA2
POLR2C
PSTPIP1
RFWD3
RMND5B
RNF10
RNF103
RNF111
RNF114
RNF115
RNF123
RNF125
RNF138
RNF14
RNF150
RNF152
RNF165
RNF166
RNF167
RNF183
RNF185
RNF2
RNF26
RNF31
RNF4
RNF5
RNF8
ROPN1
SNCA
STUB1
TOPORS
TRIM17
TRIM2
TRIM21
TRIM23
TRIM27
TRIM31
TRIM35
TRIM39
TRIM5
TRIM59
TRIM8
UBA1
UBOX5
UFM1
UHRF2
USHBP1
XIAP
ZNRF1
ZNRF4
Entrez ID
51283
55284
HPRD ID
16548
07724
Ensembl ID
ENSG00000103429
ENSG00000104343
Uniprot IDs
H3BMP2
Q9NZS9
Q96B02
Q96FI0
X6REH9
PDB IDs
2A7L
2MT6
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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