PDZD11 and CD79B

Data Source:
BioGRID (pull down)

		PDZD11	CD79B
Description		PDZ domain containing 11	CD79b molecule
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse	Nucleoplasm Cytosol Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane B Cell Receptor Complex Extracellular Exosome
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding
	Biological Process	Biotin Metabolic Process Neurotransmitter Secretion Pantothenate Metabolic Process Antimicrobial Humoral Response Ion Transmembrane Transport Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Transmembrane Transport Protein Localization To Basolateral Plasma Membrane	Adaptive Immune Response Immune Response Signal Transduction B Cell Differentiation B Cell Receptor Signaling Pathway
Pathways		Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases	CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs			Polatuzumab vedotin
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS			Height ( 25282103)
Interacting Genes		5 interacting genes: ATP2B2 ATP7A MAGI2 PLEKHA5 SIGMAR1	14 interacting genes: BLK CD19 CD3E CD5 CD79A FYN LCK LYN PTK2 PTPN6 SGTA SGTB SYK ZAP70
Entrez ID		51248	974
HPRD ID		06622	00922
Ensembl ID		ENSG00000120509	ENSG00000007312
Uniprot IDs		Q5EBL8	P40259
PDB IDs			3KG5
Enriched GO Terms of Interacting Partners?
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