PDZD11 and RAB11FIP2

Data Source:
BioGRID (two hybrid)

		PDZD11	RAB11FIP2
Description		PDZ domain containing 11	RAB11 family interacting protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Cell-cell Junction Adherens Junction Basolateral Plasma Membrane Synapse Pore Complex Presynapse	Phagocytic Cup Nucleoplasm Endosome Cytoplasmic Vesicle Membrane Cell Projection Intracellular Membrane-bounded Organelle Recycling Endosome Membrane
	Molecular Function	Protein Binding	Protein Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Biotin Metabolic Process Neurotransmitter Secretion Pantothenate Metabolic Process Antimicrobial Humoral Response Ion Transmembrane Transport Maintenance Of Epithelial Cell Apical/basal Polarity Pore Complex Assembly Transmembrane Transport Protein Localization To Basolateral Plasma Membrane	Renal Water Homeostasis Phagocytosis Establishment Of Cell Polarity TRAM-dependent Toll-like Receptor 4 Signaling Pathway Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of GTPase Activity Regulated Exocytosis Positive Regulation Of Protein Localization To Plasma Membrane
Pathways		Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases	Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS			Age spots ( 29895819) Asthma (sex interaction) ( 24824216) Celiac disease ( 23936387) Freckles ( 29895819) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Serum uric acid levels ( 30993211 29403010)
Interacting Genes		5 interacting genes: ATP2B2 ATP7A MAGI2 PLEKHA5 SIGMAR1	20 interacting genes: AP2A1 CXCR2 EHD1 FAM90A1 FBXO17 FKBP6 HSF2BP ITSN1 KANK2 LRRK2 MARK2 MYO5B PIBF1 RAB11A RAB11B RAB11FIP4 RAB25 REPS1 YWHAE YWHAG
Entrez ID		51248	22841
HPRD ID		06622	10548
Ensembl ID		ENSG00000120509	ENSG00000107560
Uniprot IDs		Q5EBL8	Q7L804
PDB IDs			2GZD 2GZH 2K6S 3TSO 4C4P 6S8X
Enriched GO Terms of Interacting Partners?
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