MZB1 and CASP2

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MZB1	CASP2
Description		marginal zone B and B1 cell specific protein	caspase 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Lumen Endoplasmic Reticulum Chaperone Complex	Nucleus Cytoplasm Mitochondrion Cytosol Membrane
	Molecular Function	Protein Binding	Cysteine-type Endopeptidase Activity Protein Binding Enzyme Binding Protein Domain Specific Binding Identical Protein Binding Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Cysteine-type Endopeptidase Activity Involved In Execution Phase Of Apoptosis
	Biological Process	Positive Regulation Of Immunoglobulin Production Apoptotic Process Positive Regulation Of Cell Population Proliferation Regulation Of B Cell Proliferation Integrin Activation Regulation Of Cell Population Proliferation Regulation Of Insulin Receptor Signaling Pathway	Luteolysis Neural Retina Development Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Brain Development Aging Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Processing Ectopic Germ Cell Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Neuron Apoptotic Process Cellular Response To Mechanical Stimulus Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Execution Phase Of Apoptosis Positive Regulation Of Apoptotic Signaling Pathway
Pathways			NOD1/2 Signaling Pathway NADE modulates death signalling TP53 Regulates Transcription of Caspase Activators and Caspases
Drugs
Diseases
GWAS		Body mass index ( 26426971) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Malaria ( 31844061)
Interacting Genes		4 interacting genes: CASP2 CASP9 MAPK6 TSG101	31 interacting genes: ADCYAP1 BAG4 BID CASP10 CASP14 CASP3 CASP7 CASP8 CCND3 CFLAR CRADD CSNK2A1 DCTN1 DSP EEF1A1 GOLGA3 GRB2 KPNA2 MDM2 MZB1 NLRP1 NOD1 NOL3 PIDD1 PRKAB2 RAI1 RB1 RPL30 RXRA SUMO1 UBE2I
Entrez ID		51237	835
HPRD ID		17815	02800
Ensembl ID		ENSG00000170476	ENSG00000106144
Uniprot IDs		Q8WU39	A0A087WYM1 A0A0S2Z3H1 D3DXD9 P42575
PDB IDs			1PYO 2P2C 3R5J 3R6G 3R6L 3R7B 3R7N 3R7S 3RJM 6GKF 6GKG 6S9K 6SAD
Enriched GO Terms of Interacting Partners?
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