IPO11 and RPL12

Data Source:
HPRD (in vivo)

		IPO11	RPL12
Description		importin 11	ribosomal protein L12
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nucleoplasm Cytosol	Cytosol Focal Adhesion Postsynaptic Density Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit Extracellular Exosome
	Molecular Function	Protein Binding Nuclear Import Signal Receptor Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding Large Ribosomal Subunit RRNA Binding
	Biological Process	Protein Import Into Nucleus Ribosomal Protein Import Into Nucleus	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 23216389) Diffusing capacity of the lung for carbon monoxide traits ( 30049742) General risk tolerance (MTAG) ( 30643258) Interstitial lung abnormalities ( 31339356) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Subpleural-predominant interstitial lung abnormalities ( 31339356)
Interacting Genes		12 interacting genes: C1orf94 EIF4A2 KEAP1 KRT76 NXF1 PLCD4 RAN RPL12 TRAF2 UBE2E1 UBE2E2 UBE2E3	9 interacting genes: APP CBX1 DUX4 IPO11 OR10G4 PAXIP1 PTEN TTN UBC
Entrez ID		51194	6136
HPRD ID		10003	01603
Ensembl ID		ENSG00000086200	ENSG00000197958
Uniprot IDs		Q9UI26	P30050
PDB IDs			4V6X 5A8L 5AJ0 6OLG 6ZM7 6ZME 6ZMI 6ZMO
Enriched GO Terms of Interacting Partners?
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