PDCL and TCP1

Data Source:
HPRD (in vitro)

		PDCL	TCP1
Description		phosducin like	t-complex 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cilium	Pericentriolar Material Heterochromatin Acrosomal Vesicle Zona Pellucida Receptor Complex Golgi Apparatus Centrosome Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome
	Molecular Function	Protein Binding Protein-containing Complex Binding	RNA Binding Protein Binding ATP Binding Ubiquitin Protein Ligase Binding Protein Folding Chaperone Unfolded Protein Binding
	Biological Process	Protein Folding Signal Transduction Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Cell Projection Organization Positive Regulation Of Smoothened Signaling Pathway Negative Regulation Of Protein Refolding Heterotrimeric G-protein Complex Assembly	Protein Folding Tubulin Complex Assembly Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Interleukin-12-mediated Signaling Pathway Translocation Of Peptides Or Proteins Into Host Cell Cytoplasm Protein Stabilization Positive Regulation Of Telomerase Activity ScaRNA Localization To Cajal Body Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body Regulation Of Macrophage Apoptotic Process
Pathways		Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis BBSome-mediated cargo-targeting to cilium Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		11 interacting genes: CCT3 CCT5 GNB1 GNGT1 GRK2 IKBKG LRRK2 MFHAS1 MRPL11 PSMC5 TCP1	14 interacting genes: CBFA2T2 CCT5 CCT7 CDC20 DUX4 FANCA PDCL PTEN SH3BP4 SUMO2 TUBA4A TUBA8 VRK2 YWHAQ
Entrez ID		5082	6950
HPRD ID		05108	01748
Ensembl ID		ENSG00000136940	ENSG00000120438
Uniprot IDs		Q13371	E7EQR6 P17987
PDB IDs			6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8
Enriched GO Terms of Interacting Partners?
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