MYL4 and LOX

Data Source:
BioGRID (affinity chromatography technology)

		MYL4	LOX
Description		myosin light chain 4	lysyl oxidase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Myosin Complex A Band	Extracellular Region Collagen Trimer Extracellular Space Nucleus Extracellular Matrix
	Molecular Function	Actin Monomer Binding Calcium Ion Binding Myosin II Heavy Chain Binding Actin Filament Binding	Protein-lysine 6-oxidase Activity Copper Ion Binding Protein Binding Collagen Binding
	Biological Process	Regulation Of The Force Of Heart Contraction Muscle Filament Sliding Positive Regulation Of ATPase Activity Cardiac Muscle Contraction	Osteoblast Differentiation Regulation Of Protein Phosphorylation Cellular Protein Modification Process Heart Development Regulation Of Gene Expression Regulation Of Striated Muscle Tissue Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Peptidyl-lysine Oxidation Protein Phosphopantetheinylation Extracellular Matrix Organization Collagen Fibril Organization Bone Mineralization Lung Development Platelet-derived Growth Factor Receptor-beta Signaling Pathway Ascending Aorta Development Descending Aorta Development Wound Healing Response To Drug Regulation Of Apoptotic Process Protein Kinase B Signaling Regulation Of Megakaryocyte Differentiation Muscle Cell Cellular Homeostasis Elastic Fiber Assembly Blood Vessel Morphogenesis Response To Steroid Hormone Muscle Fiber Development Cell Chemotaxis Connective Tissue Development DNA Biosynthetic Process Regulation Of Receptor Binding Regulation Of Bone Development Cellular Response To Chemokine Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway
Pathways		Striated Muscle Contraction	Elastic fibre formation Crosslinking of collagen fibrils
Drugs
Diseases
GWAS		Body mass index ( 26426971) Erythema nodosum in inflammatory bowel disease ( 24487271)	Central corneal thickness ( 32528159) Coronary artery disease ( 28714974) Intraocular pressure ( 29617998) Lung function (FEV1/FVC) ( 30804560) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		1 interacting genes: PYROXD2	8 interacting genes: DHDDS DPT ELN H1-1 H1-5 H2BC11 H2BC21 RAF1
Entrez ID		4635	4015
HPRD ID		01176	01087
Ensembl ID		ENSG00000198336	ENSG00000113083
Uniprot IDs		P12829	B0AZT2 B7ZAJ4 D0PNI2 P28300
PDB IDs
Enriched GO Terms of Interacting Partners?
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