SERPINC1 and FMO3

Data Source:
HPRD (in vitro)

		SERPINC1	FMO3
Description		serpin family C member 1	flavin containing dimethylaniline monoxygenase 3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Blood Microparticle	Endoplasmic Reticulum Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Identical Protein Binding	Monooxygenase Activity N,N-dimethylaniline Monooxygenase Activity Protein Binding Trimethylamine Monooxygenase Activity Flavin Adenine Dinucleotide Binding NADP Binding
	Biological Process	Acute Inflammatory Response To Antigenic Stimulus Response To Nutrient Lactation Blood Coagulation Negative Regulation Of Endopeptidase Activity Post-translational Protein Modification Cellular Protein Metabolic Process Regulation Of Blood Coagulation, Intrinsic Pathway	Xenobiotic Metabolic Process
Pathways		Intrinsic Pathway of Fibrin Clot Formation Common Pathway of Fibrin Clot Formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	FMO oxidises nucleophiles Defective FMO3 causes Trimethylaminuria (TMAU)
Drugs		Ardeparin Fondaparinux Heparin Enoxaparin N-Formylmethionine SR-123781A Sulodexide Danaparoid Dalteparin Tinzaparin Nadroparin Copper Protamine sulfate Bemiparin Antithrombin III human
Diseases		Inherited thrombophilia
GWAS		Experiencing mood swings ( 29500382) Heel bone mineral density ( 30598549)	Blood metabolite levels ( 24816252) Lentiform nucleus volume ( 22903471)
Interacting Genes		6 interacting genes: F2 KLK1 KLK2 KLK6 PLG SDC2	4 interacting genes: CLEC10A CREB3 SACM1L SGSM3
Entrez ID		462	2328
HPRD ID		00122	00633
Ensembl ID		ENSG00000117601	ENSG00000007933
Uniprot IDs		A0A024R944 P01008	A0A024R8Z4 B7Z3M2 B7Z543 P31513 Q53FW5
PDB IDs		1ANT 1ATH 1AZX 1BR8 1DZG 1DZH 1E03 1E04 1E05 1JVQ 1LK6 1NQ9 1OYH 1R1L 1SR5 1T1F 1TB6 2ANT 2B4X 2B5T 2BEH 2GD4 2HIJ 2ZNH 3EVJ 3KCG 4EB1
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?