MLLT1 and NFIX

Data Source:
BioGRID (proximity labelling technology)

		MLLT1	NFIX
Description		MLLT1 super elongation complex subunit	nuclear factor I X
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytosol Transcription Elongation Factor Complex	Chromatin Nucleus
	Molecular Function	Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Protein Kinase Activity	Negative Regulation Of Transcription By RNA Polymerase II DNA Replication Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Formation of RNA Pol II elongation complex RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation	RNA Polymerase III Transcription Termination RNA Polymerase III Abortive And Retractive Initiation
Drugs
Diseases		Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Monocyte percentage of white cells ( 32888494) Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder ( 27021288)	Bipolar disorder ( 28115744) Body mass index ( 25673413) Brain morphology (MOSTest) ( 32665545) Clozapine-induced agranulocytosis ( 25187353) Granulocyte percentage of myeloid white cells ( 27863252) Heel bone mineral density ( 30598549) Hemoglobin ( 32888494) Intelligence (MTAG) ( 29326435) Lymphocyte counts ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Monocyte count ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		12 interacting genes: AFF1 AFF4 ALKBH4 ARID1A BMI1 CBX8 H1-5 H3-4 MLLT10 PAF1 WDR5 YIF1A	8 interacting genes: JMJD6 MLH1 NFIB PIR QRICH1 RFX1 SKI ZNF614
Entrez ID		4298	4784
HPRD ID		15933	01234
Ensembl ID		ENSG00000130382	ENSG00000008441
Uniprot IDs		Q03111	B4DHW2 Q14938
PDB IDs		5J9S 6HPW 6HPX 6HPY 6HPZ 6HQ0 6HT0 6HT1 6T1I 6T1J 6T1L 6T1M 6T1N 6T1O
Enriched GO Terms of Interacting Partners?
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