MIR140 and CRTAP

Data Source:
BioGRID (unspecified method)

		MIR140	CRTAP
Description		microRNA 140	cartilage associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Protein-containing Complex
	Molecular Function	RNA Polymerase II Complex Binding MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing	Protein Binding Collagen Binding
	Biological Process	Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of BMP Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Interleukin-6 Production Negative Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Gene Silencing By MiRNA Defense Response To Bacterium Cellular Response To Lipopolysaccharide Cellular Response To Hypoxia Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Vascular Endothelial Growth Factor Production Cellular Response To Amyloid-beta Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching	Spermatogenesis Peptidyl-proline Hydroxylation To 3-hydroxy-L-proline Collagen Fibril Organization Protein Stabilization Chaperone-mediated Protein Folding Negative Regulation Of Post-translational Protein Modification
Pathways			Collagen biosynthesis and modifying enzymes
Drugs
Diseases			Osteogenesis imperfecta
GWAS		Body mass index ( 26426971)	Asthma ( 31959851 31619474) Major depressive disorder ( 29317602) Multiple sclerosis ( 31604244) Refractive error ( 32231278) Retinal detachment or retinal break ( 31816047)
Interacting Genes		68 interacting genes: ADARB1 AIMP1 APOBEC3B C1QBP CELF1 CELF2 CRTAP CSTF1 DARS1 DDX1 DDX21 DDX3X DDX49 EIF2AK2 EPRS1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LIN28A LRPPRC MARS1 MATR3 NOL6 NONO NUDT21 PDCD11 PIKFYVE PIP5K1A PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM14 RTCB SF3B1 SF3B3 SFPQ SYNCRIP TAF15 TRA2A TRA2B UPF1 UTP20 YBX1 YBX3	24 interacting genes: MIR1-1 MIR10B MIR128-1 MIR138-2 MIR140 MIR16-1 MIR16-2 MIR17 MIR18A MIR199A2 MIR19A MIR19B1 MIR200B MIR200C MIR20A MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIRLET7B MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I
Entrez ID		406932	10491
HPRD ID			16110
Ensembl ID		ENSG00000208017	ENSG00000170275
Uniprot IDs			O75718
PDB IDs
Enriched GO Terms of Interacting Partners?
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