MIR138-1 and IGF2BP3

Data Source:
BioGRID (unspecified method)

		MIR138-1	IGF2BP3
Description		microRNA 138-1	insulin like growth factor 2 mRNA binding protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Cytosol
	Molecular Function	MRNA Binding Involved In Posttranscriptional Gene Silencing	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Translation Regulator Activity MRNA 5'-UTR Binding
	Biological Process	Negative Regulation Of Cell Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Osteoblast Proliferation Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Phosphatidylinositol 3-kinase Activity Plasma Membrane Raft Assembly Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Response To Cytokine Stimulus Negative Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of P38MAPK Cascade Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Cytokine Production Translation Nervous System Development Anatomical Structure Morphogenesis Regulation Of Gene Expression Negative Regulation Of Translation Regulation Of MRNA Stability MRNA Transport Regulation Of RNA Metabolic Process
Pathways			Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA
Drugs
Diseases
GWAS		Schizophrenia ( 30285260)	Birth weight ( 31043758 27680694) Height ( 28552196 20881960 25282103 23563607) Hip circumference adjusted for BMI ( 25673412) Infant length ( 25281659) Offspring birth weight ( 31043758) Personality dimensions ( 23903073) Type 2 diabetes ( 30297969) White blood cell count ( 32888494)
Interacting Genes		67 interacting genes: ADARB1 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LRPPRC MARS1 MATR3 NONO NUDT16L1 NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3	76 interacting genes: DUX4 MEOX2 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PCBP1 PIH1D2
Entrez ID		406929	10643
HPRD ID			16306
Ensembl ID		ENSG00000207954	ENSG00000136231
Uniprot IDs			O00425
PDB IDs			2E44 6FQ1 6FQR 6GQE 6GX6
Enriched GO Terms of Interacting Partners?
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