LBP and CTNNBL1

Data Source:
BioGRID (affinity chromatography technology)

		LBP	CTNNBL1
Description		lipopolysaccharide binding protein	catenin beta like 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Membrane Extracellular Exosome	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Centrosome Cytosol Membrane
	Molecular Function	Lipopolysaccharide Binding Signaling Receptor Binding Protein Binding Lipoteichoic Acid Binding Lipopeptide Binding	Protein Binding Enzyme Binding
	Biological Process	Toll-like Receptor Signaling Pathway Leukocyte Chemotaxis Involved In Inflammatory Response Macrophage Activation Involved In Immune Response Acute-phase Response Cellular Defense Response Opsonization Lipopolysaccharide Transport Cytokine-mediated Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Detection Of Molecule Of Bacterial Origin Response To Lipopolysaccharide Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Macromolecule Localization Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Macrophage Activation Innate Immune Response Positive Regulation Of Cytolysis Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Cellular Response To Lipopolysaccharide Cellular Response To Lipoteichoic Acid Positive Regulation Of Neutrophil Chemotaxis	MRNA Splicing, Via Spliceosome Apoptotic Process Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process
Pathways		Toll Like Receptor 4 (TLR4) Cascade Transfer of LPS from LBP carrier to CD14 Regulation of TLR by endogenous ligand Interleukin-4 and Interleukin-13 signaling	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Basophil percentage of white cells ( 32888494) Blood protein levels ( 29875488) Periodontitis (DPAL) ( 24024966)	Body size at age 10 ( 32376654) Bone mineral density ( 17903296) California verbal learning test score ( 31596458) Falling risk ( 32999390)
Interacting Genes		18 interacting genes: APOA1 BAG6 BST1 C4BPA CAMP CBFA2T2 CD14 CFHR1 FTH1 HSPB1 PRDX4 PSMA3 PYCR3 RPS21 SETD1A SMAD3 TRA2A TSC22D4	27 interacting genes: BEX3 BUD31 CALCOCO1 CATIP CDC5L CDCA7L CREBZF CWC15 HMGB1 HNRNPK IK LDOC1 LUC7L MAPK8IP2 MED4 MEOX2 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP SUMO2 U2SURP WBP11 ZCCHC10
Entrez ID		3929	56259
HPRD ID		07175	10850
Ensembl ID		ENSG00000129988	ENSG00000132792
Uniprot IDs		P18428 Q8TCF0	Q8WYA6
PDB IDs			4CB8 4CB9 4CBA 4HM9 4HNM 4MFU 4MFV
Enriched GO Terms of Interacting Partners?
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