KIF2A and KLC2

Data Source:
HPRD (in vivo)

		KIF2A	KLC2
Description		kinesin family member 2A	kinesin light chain 2
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GO Annotations	Cellular Component	Spindle Pole Nucleoplasm Nucleolus Cytoplasm Centrosome Centriole Spindle Cytosol Kinesin Complex Microtubule Spindle Microtubule Membrane Nuclear Body Centriolar Subdistal Appendage	Nucleoplasm Mitochondrion Cytosol Kinesin Complex Microtubule Plasma Membrane Membrane Kinesin I Complex Protein-containing Complex
	Molecular Function	Motor Activity Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATPase Activity	Protein Binding Kinesin Binding Cadherin Binding
	Biological Process	Microtubule Cytoskeleton Organization Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Microtubule Depolymerization Mitotic Spindle Organization Nervous System Development Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Differentiation Regulation Of Cell Migration Cell Division Mitotic Spindle Assembly	Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Microtubule-based Movement Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins	MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins
Drugs
Diseases
GWAS		Diastolic blood pressure ( 30224653) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483)	Bipolar disorder ( 21926972 31043756) Metabolite levels ( 23823483)
Interacting Genes		13 interacting genes: CASK CLSTN1 DYNLT1 FAM13C FXR2 H3-4 KLC1 KLC2 LARP1B LMO2 LMO3 MRPL53 SUMO2	16 interacting genes: AIMP2 APP CLSTN1 COIL DDX41 KIF2A KLC1 KLC4 LRRK2 MAPK8IP3 PIK3R3 PRC1 S100A8 YWHAG YWHAQ YWHAZ
Entrez ID		3796	64837
HPRD ID		03996	13917
Ensembl ID		ENSG00000068796	ENSG00000174996
Uniprot IDs		A0A6Q8PFA6 B0AZS5 O00139	Q9H0B6
PDB IDs		2GRY 6BBN	3CEQ 3EDT
Enriched GO Terms of Interacting Partners?
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