Wiki-Pi
About
Search
Browse
People
Updates
Search
KCNE1 and CBR3
Data Source:
BioGRID
(affinity chromatography technology)
KCNE1
CBR3
Description
potassium voltage-gated channel subfamily E regulatory subunit 1
carbonyl reductase 3
Image
GO Annotations
Cellular Component
Lysosome
Plasma Membrane
Voltage-gated Potassium Channel Complex
Cell Surface
Apical Plasma Membrane
Z Disc
Membrane Raft
Extracellular Space
Nucleoplasm
Cytosol
Molecular Function
Voltage-gated Potassium Channel Activity
Delayed Rectifier Potassium Channel Activity
Protein Binding
Potassium Channel Regulator Activity
Telethonin Binding
Ion Channel Binding
Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization
Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
3-keto Sterol Reductase Activity
Carbonyl Reductase (NADPH) Activity
Protein Binding
NADPH Binding
Biological Process
Sensory Perception Of Sound
Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization
Cardiac Conduction
Cellular Response To CAMP
Potassium Ion Transmembrane Transport
Cardiac Muscle Cell Action Potential Involved In Contraction
Ventricular Cardiac Muscle Cell Action Potential
Membrane Repolarization
Membrane Repolarization During Action Potential
Membrane Repolarization During Cardiac Muscle Cell Action Potential
Regulation Of Heart Rate By Cardiac Conduction
Negative Regulation Of Protein Targeting To Membrane
Potassium Ion Export Across Plasma Membrane
Membrane Repolarization During Ventricular Cardiac Muscle Cell Action Potential
Regulation Of Potassium Ion Transmembrane Transport
Positive Regulation Of Potassium Ion Transmembrane Transport
Regulation Of Delayed Rectifier Potassium Channel Activity
Negative Regulation Of Delayed Rectifier Potassium Channel Activity
Xenobiotic Metabolic Process
Phylloquinone Catabolic Process
Cognition
Pathways
Phase 3 - rapid repolarisation
Phase 2 - plateau phase
Phase I - Functionalization of compounds
Drugs
Enflurane
Promethazine
Miconazole
Azimilide
Diseases
Long QT syndrome, including: Romano-Ward syndrome; Jervell and Lange-Nielsen syndrome (JLNS)
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Electrocardiographic traits (
32602732
20062063
)
Hippocampal volume (
29274321
)
L-selectin levels (
25576479
)
Long QT syndrome (
32429735
)
QT interval (
30679814
29213071
24952745
31217584
)
Blood protein levels (
30072576
29875488
)
Lumbar spine bone mineral density (
22504420
)
Interacting Genes
6 interacting genes:
ADRB2
KCNH2
KCNQ1
PRKCA
TPM3
UBASH3A
5 interacting genes:
ARIH2
BICD2
RAB35
SDCBP
UBC
Entrez ID
3753
874
HPRD ID
01442
07222
Ensembl ID
ENSG00000180509
ENSG00000159231
Uniprot IDs
A7LFK2
A7LFK4
C7S316
P15382
Q6FHJ6
O75828
V9HW40
PDB IDs
2K21
2HRB
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?