HSF4 and YTHDF1

Data Source:
BioGRID (two hybrid)

		HSF4	YTHDF1
Description		heat shock transcription factor 4	YTH N6-methyladenosine RNA binding protein 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nuclear Speck	Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Identical Protein Binding Sequence-specific Double-stranded DNA Binding	RNA Binding MRNA Binding Protein Binding Ribosome Binding N6-methyladenosine-containing RNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Visual Perception Positive Regulation Of Cell Population Proliferation Histone H3-K9 Demethylation Camera-type Eye Development Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Cell Development	Immune System Process Regulation Of Antigen Processing And Presentation Learning Memory Positive Regulation Of Translation Positive Regulation Of Translational Initiation MRNA Destabilization Regulation Of Long-term Synaptic Potentiation Regulation Of Axon Guidance
Pathways
Drugs
Diseases
GWAS			Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Interacting Genes		43 interacting genes: AKAP8L ALKBH4 C10orf55 C19orf54 CDK2AP2 DAXX DUSP26 FAM168B FOXH1 FOXI1 GFOD1 HGS INTS11 KRT31 KRT37 KRT38 KRT40 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP6-2 MAPK1 MAPK14 MAPK3 MAPK8 MKRN3 NHLRC4 NUDT21 NUP62 OIP5 PIH1D2 PITX1 PLA2G10 PPFIBP2 SESTD1 SLC27A5 SMARCA4 SOX10 TPM3 UFSP1 YTHDF1 ZBED8 ZMYND12	19 interacting genes: ABHD11 BATF2 C6orf15 FAM168A HEY1 HSF4 ITSN2 KRTAP13-1 KRTAP26-1 KRTAP7-1 KRTAP8-1 LASP1 MAGED1 MSX2 OIP5 PRR32 TLE5 VPS37C ZNF34
Entrez ID		3299	54915
HPRD ID		03896	11691
Ensembl ID		ENSG00000102878	ENSG00000149658
Uniprot IDs		A0A024R6X7 Q9ULV5	Q9BYJ9
PDB IDs		6J6V 6J6W	4RCI 4RCJ
Enriched GO Terms of Interacting Partners?
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