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HMOX2 and IMMT
Data Source:
BioGRID
(two hybrid)
HMOX2
IMMT
Description
heme oxygenase 2
inner membrane mitochondrial protein
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Specific Granule Membrane
SAM Complex
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Intermembrane Space
Membrane
MICOS Complex
MIB Complex
Molecular Function
Heme Oxygenase (decyclizing) Activity
Protein Binding
Heme Binding
Metal Ion Binding
RNA Binding
Protein Binding
Biological Process
Response To Hypoxia
Heme Oxidation
Cellular Iron Ion Homeostasis
Response To Oxidative Stress
Heme Catabolic Process
Neutrophil Degranulation
Iron Ion Homeostasis
Inner Mitochondrial Membrane Organization
Cristae Formation
Mitochondrial Calcium Ion Homeostasis
Pathways
Heme degradation
Neutrophil degranulation
Iron uptake and transport
Cristae formation
Drugs
NADH
Stannsoporfin
Diseases
GWAS
Erectile dysfunction (
30583798
)
Facial emotion recognition (sad faces) (
28608620
)
Night sleep phenotypes (
27126917
)
Interacting Genes
67 interacting genes:
A2M
APP
AQP6
ARL13B
ASGR2
ATP5F1B
BCL2L13
BLOC1S2
CCR2
CD79A
CEBPZ
CEP126
COPS6
CRB3
CSNK2A1
EBP
EEF1G
EIF3C
ELOVL4
ELOVL5
ERGIC3
F2RL1
FAM209A
FAM210B
GET1
GIT1
GPR152
GPRASP1
GPX8
HAP1
IMMT
INPP5K
ITFG1
JADE1
KCNJ6
KCNMA1
LAPTM5
LMNA
LRIF1
MED31
MGST3
MTNR1A
NDUFS2
NKRF
NR3C1
PLXNB2
PTGER4
RBBP4
RETREG3
RNASEK
SAR1A
SETDB1
SGPL1
SHC1
SKA2
SLC30A8
SMO
SNX5
SNX7
SSMEM1
STOM
SYT1
TMEM14B
TMX2
VMA21
ZFP28
ZNF746
58 interacting genes:
AKTIP
ALB
ANTKMT
ARMCX3
ASCC2
ATXN1
BAG6
BMI1
C10orf88
C8orf33
CALM1
CCDC113
CCT5
CDC37
CHD3
CSTF2
DISC1
ECSIT
EEF1A1
EP300
EXOSC10
FEZ1
FUBP1
HAP1
HIVEP1
HJURP
HMOX2
HNRNPD
HTRA2
KDM1A
KIF22
KPNA2
LRIF1
MRPL44
NDEL1
NDUFB9
NEK2
NIPSNAP3A
NOS3
PFDN1
PIAS4
PLA2G15
PPOX
PRRC2A
RER1
SDHAF2
SMN1
SNAPIN
SRRT
STMN4
STX5
TAF1D
TK1
TNNT1
TRAF3IP1
TUBGCP3
TXNDC9
UBQLN4
Entrez ID
3163
10989
HPRD ID
00783
02658
Ensembl ID
ENSG00000103415
ENSG00000132305
Uniprot IDs
A0A087WT44
B3KSE0
P30519
Q16891
PDB IDs
2Q32
2QPP
2RGZ
4WMH
5UC8
5UC9
5UCA
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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