DPP7 and NPHP3

Data Source:
BioGRID (affinity chromatography technology)

		DPP7	NPHP3
Description		dipeptidyl peptidase 7	nephrocystin 3
Image
GO Annotations	Cellular Component	Extracellular Region Golgi Apparatus Cytosol Vesicle Azurophil Granule Lumen Intracellular Membrane-bounded Organelle Extracellular Exosome	Extracellular Region Cytosol Cilium
	Molecular Function	Aminopeptidase Activity Serine-type Peptidase Activity Dipeptidyl-peptidase Activity	Protein Binding
	Biological Process	Proteolysis Neutrophil Degranulation	Kidney Development Heart Looping Atrial Septum Development Determination Of Left/right Symmetry Wnt Signaling Pathway Lung Development Determination Of Pancreatic Left/right Asymmetry Photoreceptor Cell Maintenance Maintenance Of Animal Organ Identity Convergent Extension Involved In Gastrulation Cilium Assembly Epithelial Cilium Movement Involved In Determination Of Left/right Asymmetry Kidney Morphogenesis Determination Of Intestine Left/right Asymmetry Determination Of Stomach Left/right Asymmetry Determination Of Liver Left/right Asymmetry Ureter Development Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Planar Cell Polarity Pathway Involved In Neural Tube Closure
Pathways		Neutrophil degranulation	Trafficking of myristoylated proteins to the cilium
Drugs
Diseases			Senior-Loken syndrome Renal-hepatic-pancreatic dysplasia Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2) Meckel syndrome (MKS); Meckel-Gruber syndrome
GWAS		Blood protein levels ( 29875488) Pursuit maintenance gain ( 29064472)	Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Menarche (age at onset) ( 27182965 21102462) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		1 interacting genes: XRN1	3 interacting genes: ATXN1 DYSF NPHP1
Entrez ID		29952	27031
HPRD ID		07634	06417
Ensembl ID		ENSG00000176978	ENSG00000113971
Uniprot IDs		Q9UHL4	Q7Z494
PDB IDs		3JYH 3N0T 4EBB	5L7K
Enriched GO Terms of Interacting Partners?
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