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DPP7 and CSF2
Data Source:
BioGRID
(biochemical)
DPP7
CSF2
Description
dipeptidyl peptidase 7
colony stimulating factor 2
Image
GO Annotations
Cellular Component
Extracellular Region
Golgi Apparatus
Cytosol
Vesicle
Azurophil Granule Lumen
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Extracellular Region
Extracellular Space
Intracellular Membrane-bounded Organelle
Molecular Function
Aminopeptidase Activity
Serine-type Peptidase Activity
Dipeptidyl-peptidase Activity
Cytokine Activity
Granulocyte Macrophage Colony-stimulating Factor Receptor Binding
Protein Binding
Growth Factor Activity
Biological Process
Proteolysis
Neutrophil Degranulation
MAPK Cascade
Histamine Secretion
Embryonic Placenta Development
Immune Response
Positive Regulation Of Cell Population Proliferation
Positive Regulation Of Gene Expression
Positive Regulation Of Macrophage Derived Foam Cell Differentiation
Cytokine-mediated Signaling Pathway
Myeloid Cell Differentiation
Neutrophil Differentiation
Monocyte Differentiation
Macrophage Differentiation
Positive Regulation Of Interleukin-23 Production
Response To Silicon Dioxide
Response To Fluid Shear Stress
Epithelial Fluid Transport
Macrophage Activation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Myeloid Dendritic Cell Differentiation
Regulation Of Circadian Sleep/wake Cycle, Sleep
Regulation Of Myeloid Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Cellular Response To Lipopolysaccharide
Positive Regulation Of Podosome Assembly
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Dendritic Cell Differentiation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Neutrophil degranulation
Interleukin-3, Interleukin-5 and GM-CSF signaling
RAF/MAP kinase cascade
Interleukin-10 signaling
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
Interleukin receptor SHC signaling
Drugs
KB002
Diseases
GWAS
Blood protein levels (
29875488
)
Pursuit maintenance gain (
29064472
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Crohn's disease (
28067908
)
Inflammatory bowel disease (
28067908
23128233
)
Rheumatoid arthritis (
30423114
22446963
24390342
)
Subcortical volume (MOSTest) (
32665545
)
Ulcerative colitis (
28067908
)
Interacting Genes
1 interacting genes:
XRN1
7 interacting genes:
CSF2RA
CSF2RB
IL3RA
KITLG
MEOX2
PRG2
SDC2
Entrez ID
29952
1437
HPRD ID
07634
00734
Ensembl ID
ENSG00000176978
ENSG00000164400
Uniprot IDs
Q9UHL4
P04141
PDB IDs
3JYH
3N0T
4EBB
1CSG
2GMF
4NKQ
4RS1
5C7X
5D70
5D71
5D72
6BFQ
6BFS
Enriched GO Terms of Interacting Partners
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