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MLNR and GHRHR
Data Source:
HPRD
(in vivo)
MLNR
GHRHR
Description
motilin receptor
growth hormone releasing hormone receptor
Image
No pdb structure
GO Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Nuclear Inner Membrane
Nuclear Outer Membrane
Cytoplasm
Plasma Membrane
Cell Surface
Integral Component Of Membrane
Nuclear Matrix
Secretory Granule
Sarcolemma
Molecular Function
G Protein-coupled Peptide Receptor Activity
Hormone Binding
G Protein-coupled Receptor Activity
Protein Binding
G Protein-coupled Peptide Receptor Activity
Growth Hormone-releasing Hormone Receptor Activity
Peptide Hormone Binding
Growth Factor Binding
Biological Process
G Protein-coupled Receptor Signaling Pathway
Cell Surface Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Activation Of Adenylate Cyclase Activity
Lactation
Positive Regulation Of Cell Population Proliferation
Determination Of Adult Lifespan
CAMP-mediated Signaling
Water Homeostasis
Response To Insulin
Cellular Response To Insulin Stimulus
Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Multicellular Organism Growth
Hormone Metabolic Process
Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Response To Estrogen
Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
Cell Maturation
Multicellular Organismal Reproductive Process
Regulation Of Protein Metabolic Process
Response To Glucocorticoid
Positive Regulation Of Growth Hormone Secretion
Somatotropin Secreting Cell Development
Cellular Response To Glucose Stimulus
Pathways
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (s) signalling events
Glucagon-type ligand receptors
ADORA2B mediated anti-inflammatory cytokines production
Drugs
Erythromycin
Mitemcinal
Sermorelin
Tesamorelin
Diseases
Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS
Interacting Genes
4 interacting genes:
GHRHR
GHRL
GPRASP1
MLN
3 interacting genes:
GHRH
GHRL
MLNR
Entrez ID
2862
2692
HPRD ID
04197
00748
Ensembl ID
ENSG00000102539
ENSG00000106128
Uniprot IDs
O43193
A0A090N8Y6
Q02643
PDB IDs
2XDG
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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