DPH3 and ADIPOR1

Data Source:
BioGRID (two hybrid)

		DPH3	ADIPOR1
Description		diphthamide biosynthesis 3	adiponectin receptor 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Plasma Membrane Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Metal Ion Binding Adiponectin Binding Adipokinetic Hormone Receptor Activity
	Biological Process	TRNA Wobble Uridine Modification Peptidyl-diphthamide Biosynthetic Process From Peptidyl-histidine Negative Regulation Of Protein Secretion Positive Regulation Of Binding	Hormone-mediated Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Regulation Of Glucose Metabolic Process Regulation Of Lipid Metabolic Process Fatty Acid Oxidation Negative Regulation Of Cell Growth Leptin-mediated Signaling Pathway Adiponectin-activated Signaling Pathway Regulation Of Fatty Acid Biosynthetic Process Glucose Homeostasis Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Cold-induced Thermogenesis Negative Regulation Of NIK/NF-kappaB Signaling
Pathways		Synthesis of diphthamide-EEF2	AMPK inhibits chREBP transcriptional activation activity AMPK inhibits chREBP transcriptional activation activity
Drugs
Diseases
GWAS			Mean platelet volume ( 32888494 27863252)
Interacting Genes		6 interacting genes: ADIPOR1 MEOX2 PIH1D2 RPL8 SERGEF ZNF438	6 interacting genes: APPL1 DPH3 NAA20 NFKBIL1 STK11 TBXA2R
Entrez ID		285381	51094
HPRD ID		16412	06402
Ensembl ID		ENSG00000154813	ENSG00000159346
Uniprot IDs		Q96FX2	Q96A54
PDB IDs		2JR7	5LXG 6KRZ 6KS0
Enriched GO Terms of Interacting Partners?
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