CXCL17 and CCL25

Data Source:
BioGRID (pull down)

		CXCL17	CCL25
Description		C-X-C motif chemokine ligand 17	C-C motif chemokine ligand 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding	Hormone Activity Protein Binding Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Activation Of MAPK Activity Angiogenesis Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Macrophage Chemotaxis Cell Differentiation Macrophage Chemotaxis Negative Regulation Of Inflammatory Response Positive Regulation Of Monocyte Chemotaxis	Positive Regulation Of Cell-matrix Adhesion Monocyte Chemotaxis Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Neutrophil Chemotaxis Positive Regulation Of GTPase Activity Lymphocyte Chemotaxis Cell Chemotaxis Chemokine-mediated Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Interferon-gamma Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Negative Regulation Of Leukocyte Tethering Or Rolling
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399) Sphingolipid levels ( 26068415)
Interacting Genes		16 interacting genes: CCL13 CCL2 CCL20 CCL21 CCL25 CCL26 CCL28 CCL5 CCL8 CXCL10 CXCL12 CXCL14 CXCL9 PF4 XCL1 XCL2	11 interacting genes: ACKR2 ACKR4 CCL17 CCL5 CCR10 CCR9 CXCL11 CXCL12 CXCL17 PF4 PF4V1
Entrez ID		284340	6370
HPRD ID		18264	03976
Ensembl ID		ENSG00000189377	ENSG00000131142
Uniprot IDs		Q6UXB2	O15444
PDB IDs
Enriched GO Terms of Interacting Partners?
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