C12orf40 and ANO6

Data Source:
BioGRID (enzymatic study)

		C12orf40	ANO6
Description		chromosome 12 open reading frame 40	anoctamin 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytosol Plasma Membrane Cell Surface Membrane Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane
	Molecular Function	Protein Binding	Calcium Activated Cation Channel Activity Intracellular Calcium Activated Chloride Channel Activity Voltage-gated Ion Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Metal Ion Binding Protein Dimerization Activity
	Biological Process		Dendritic Cell Chemotaxis Activation Of Blood Coagulation Via Clotting Cascade Cation Transport Chloride Transport Blood Coagulation Plasma Membrane Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Ion Transmembrane Transport Positive Regulation Of Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Neutrophil Degranulation Negative Regulation Of Cell Volume Pore Complex Assembly Transmembrane Transport Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways			Stimuli-sensing channels Neutrophil degranulation
Drugs
Diseases
GWAS		Parkinson's disease ( 28011712)	Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		5 interacting genes: DYNLL1 DYNLL2 LMO4 NXF1 TNPO2
Entrez ID		283461	196527
HPRD ID		08806	18746
Ensembl ID		ENSG00000180116	ENSG00000177119
Uniprot IDs		Q86WS4	B3KX12 Q4KMQ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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