GNAL and TAF3

Data Source:
BioGRID (affinity chromatography technology)

		GNAL	TAF3
Description		G protein subunit alpha L	TATA-box binding protein associated factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Heterotrimeric G-protein Complex Plasma Membrane Extracellular Exosome	Nucleus Nucleoplasm Transcription Factor TFIID Complex Nuclear Membrane
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity Protein Binding GTP Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding	P53 Binding Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding Protein Heterodimerization Activity Transcription Regulator Inhibitor Activity
	Biological Process	Signal Transduction Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Sensory Perception Of Chemical Stimulus	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of DNA-binding Transcription Factor Activity Maintenance Of Protein Location In Nucleus Regulation Of Signal Transduction By P53 Class Mediator
Pathways		Adenylate cyclase activating pathway Adenylate cyclase inhibitory pathway Olfactory Signaling Pathway	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 27089180) Alcohol dependence ( 26365420) Metabolite levels ( 23823483) QT interval (drug interaction) ( 23459443) Sensation seeking ( 30718321) Tandem gait ( 26219847) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)	Asthma ( 31959851) Cadmium levels ( 26025379) Red blood cell count ( 32888494)
Interacting Genes			4 interacting genes: H3-4 KPNA2 KPNB1 TAF10
Entrez ID		2774	83860
HPRD ID		00758	19377
Ensembl ID		ENSG00000141404	ENSG00000165632
Uniprot IDs		A8K1Y9 P38405	Q5VWG9
PDB IDs			5C13 5WXG 5WXH 5XMY 6MZD 6MZL
Enriched GO Terms of Interacting Partners?
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