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GNAI1 and FFAR1
Data Source:
HPRD
(in vivo)
GNAI1
FFAR1
Description
G protein subunit alpha i1
free fatty acid receptor 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Lysosomal Membrane
Centrosome
Heterotrimeric G-protein Complex
Plasma Membrane
Midbody
Membrane Raft
Extracellular Exosome
Cell Cortex Region
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Magnesium Ion Binding
G Protein-coupled Receptor Binding
GTPase Activity
Protein Binding
GTP Binding
GDP Binding
G-protein Beta/gamma-subunit Complex Binding
G Protein-coupled Serotonin Receptor Binding
GTPase Activating Protein Binding
G Protein-coupled Receptor Activity
Lipid Binding
Bioactive Lipid Receptor Activity
Biological Process
Protein Folding
Cell Cycle
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Response To Peptide Hormone
Regulation Of CAMP-mediated Signaling
Negative Regulation Of Synaptic Transmission
Cell Division
Regulation Of Mitotic Spindle Organization
Cellular Response To Forskolin
Positive Regulation Of Protein Localization To Cell Cortex
G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Insulin Secretion
Positive Regulation Of Insulin Secretion
Negative Regulation Of Interleukin-1 Beta Production
Glucose Homeostasis
Positive Regulation Of Calcium Ion Transport
Response To Fatty Acid
Pathways
PLC beta mediated events
PLC beta mediated events
Adenylate cyclase inhibitory pathway
Adenylate cyclase inhibitory pathway
G-protein activation
ADP signalling through P2Y purinoceptor 12
Adrenaline,noradrenaline inhibits insulin secretion
Adrenaline,noradrenaline inhibits insulin secretion
G alpha (s) signalling events
G alpha (i) signalling events
G alpha (i) signalling events
G alpha (z) signalling events
Regulation of insulin secretion
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding
Extra-nuclear estrogen signaling
ADORA2B mediated anti-inflammatory cytokines production
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
G alpha (q) signalling events
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion
Free fatty acid receptors
Drugs
Guanosine-5'-Diphosphate
Tetrafluoroaluminate Ion
Icosapent
Diseases
GWAS
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Emphysema annual change measurement in smokers (adjusted lung density) (
31324189
)
Night sleep phenotypes (
27126917
)
Post bronchodilator FEV1 (
26634245
)
Interacting Genes
62 interacting genes:
ADCY5
ADRA2A
ADRB2
CCR5
CD47
CNR1
CRHR1
CXCR4
DRD3
DRD4
EPOR
ESR1
FFAR1
GNAO1
GNB2
GNB4
GNG2
GPR1
GPR143
GPSM1
GPSM2
GPSM3
HRH4
HTR2A
IGF1R
KLHL3
MTNR1A
MTNR1B
NGB
NUCB1
NUMA1
OPRD1
OPRM1
PCP2
PDE6D
PTEN
PTPRU
RANGAP1
RASD1
RGS10
RGS12
RGS14
RGS16
RGS17
RGS18
RGS19
RGS20
RGS4
RGS7
RIC8A
S1PR1
S1PR2
S1PR3
S1PR4
S1PR5
SSTR2
SSTR3
STRN
THAP7
TSHR
VIPR1
WASF1
2 interacting genes:
GNAI1
GNAQ
Entrez ID
2770
2864
HPRD ID
00756
04822
Ensembl ID
ENSG00000127955
ENSG00000126266
Uniprot IDs
P63096
O14842
PDB IDs
1KJY
1Y3A
2G83
2GTP
2IK8
2OM2
2XNS
3ONW
3QE0
3QI2
3UMR
3UMS
4G5Q
5JS7
5JS8
5TDH
6CMO
6CRK
6DDE
6DDF
6KPF
6KPG
6LFM
6LFO
6LML
6N4B
6OMM
6OS9
6OSA
6OT0
6PB0
6PB1
6PT0
6QNO
6VU8
6XBJ
6XBK
6XBL
6XBM
4PHU
5KW2
5TZR
5TZY
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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