ELP4 and NAGK

Data Source:
BioGRID (biochemical)

		ELP4	NAGK
Description		elongator acetyltransferase complex subunit 4	N-acetylglucosamine kinase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Transcription Elongation Factor Complex Elongator Holoenzyme Complex	Cytosol Extracellular Exosome
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding Phosphorylase Kinase Regulator Activity	Protein Binding ATP Binding N-acetylglucosamine Kinase Activity
	Biological Process	TRNA Wobble Uridine Modification Regulation Of Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter Regulation Of Protein Kinase Activity	N-acetylglucosamine Metabolic Process UDP-N-acetylglucosamine Biosynthetic Process N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Carbohydrate Phosphorylation
Pathways		HATs acetylate histones	Synthesis of UDP-N-acetyl-glucosamine
Drugs			N-Acetylglucosamine
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Glaucoma ( 25027321) Mental health study participation (completed survey) ( 31263887) Optic disc area ( 25631615) Optic disc size ( 31809533) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Blood protein levels ( 30072576 29875488 28240269) Erythema nodosum in inflammatory bowel disease ( 24487271)
Interacting Genes		2 interacting genes: HINFP PPP1CC	33 interacting genes: ACTR10 ANKRD1 CCDC158 CDKN2C CEP43 DACH1 DCP2 DYNC1I1 GNPNAT1 LACTB2 LENG1 LMO1 LNX1 LNX2 LSM8 MEOX1 MTHFD2 NTAQ1 PJA1 PKM PPHLN1 REL SDCBP SF3B3 SMAD2 SMAD9 SPRED1 SRPK2 STK16 SYNE4 TCF12 TNNT1 WDR82
Entrez ID		26610	55577
HPRD ID		07377	08441
Ensembl ID		ENSG00000109911	ENSG00000124357
Uniprot IDs		G5E9D4 Q96EB1	A0A384N6G7 C9JEV6 Q9UJ70
PDB IDs			2CH5 2CH6
Enriched GO Terms of Interacting Partners?
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