PTPN18 and ARHGAP5

		PTPN18	ARHGAP5
Description		protein tyrosine phosphatase non-receptor type 18	Rho GTPase activating protein 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Endoplasmic Reticulum Cytosol Plasma Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Protein Binding	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding SH2 Domain Binding
	Biological Process	Blastocyst Formation Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation ERBB2 Signaling Pathway Cellular Response To Cytokine Stimulus Negative Regulation Of ERBB Signaling Pathway	Cell Adhesion Rho Protein Signal Transduction Mammary Gland Development Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction
Pathways		Downregulation of ERBB2 signaling Interleukin-37 signaling	Rho GTPase cycle
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Diseases
GWAS			Asthma ( 29273806)
Interacting Genes		11 interacting genes: AATK ABL1 ARHGAP5 CSK EGFR ERBB2 GAB1 PSTPIP1 PSTPIP2 SRC TEC	11 interacting genes: ADRB2 ITGA5 ITGB1 PTK2B PTPN18 RASA1 RHOA RND1 RND2 RND3 SMURF2
Entrez ID		26469	394
HPRD ID		05961	04060
Ensembl ID		ENSG00000072135	ENSG00000100852
Uniprot IDs		Q99952	Q13017
PDB IDs		2OC3 4GFU 4GFV 4NND	2EE4 2EE5 5U4V
Enriched GO Terms of Interacting Partners?
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