OSBPL3 and PALS2

Data Source:
BioGRID (proximity labelling technology)

		OSBPL3	PALS2
Description		oxysterol binding protein like 3	protein associated with LIN7 2, MAGUK family member
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Nuclear Membrane Filopodium Tip Intracellular Membrane-bounded Organelle Perinuclear Endoplasmic Reticulum	Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Sterol Transporter Activity Cholesterol Binding Sterol Binding	Protein Binding
	Biological Process	Bile Acid Biosynthetic Process Sterol Transport	Protein-containing Complex Assembly
Pathways		Synthesis of bile acids and bile salts
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 31043756) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Pursuit maintenance gain ( 29064472) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		25 interacting genes: ACSM1 BYSL FAM161A GABARAPL1 GABARAPL2 LNX1 MCRS1 PLK4 PRPF18 PRPF3 RALGPS2 RPL11 STK35 SYTL4 TCEA2 TCEANC TRAF3IP3 WT1 YWHAB YWHAG ZBTB16 ZNF48 ZNF497 ZNF648 ZNF835	30 interacting genes: AATF ABCA1 ARHGAP18 DIS3 DNM2 DYNLRB1 EIF3G EXOSC10 EXOSC2 EXOSC4 EXOSC5 EXOSC6 EXOSC7 EXOSC8 EXOSC9 FTL KHDRBS1 KNSTRN LIN7A LIN7B LIN7C MT2P1 MTREX NDN NFKB1 PARN RPS20 SMARCA4 SNX9 THOP1
Entrez ID		26031	51678
HPRD ID		09474	09509
Ensembl ID		ENSG00000070882	ENSG00000105926
Uniprot IDs		Q9H4L5	A0A024RA25 B8ZZG1 Q9NZW5
PDB IDs		7CYZ
Enriched GO Terms of Interacting Partners?
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