ALPI and AGAP1

Data Source:
HPRD (in vivo, in vitro)

		ALPI	AGAP1
Description		alkaline phosphatase, intestinal	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Anchored Component Of Membrane	Nucleus Cytoplasm
	Molecular Function	Magnesium Ion Binding Protease Binding Alkaline Phosphatase Activity Protein Binding Zinc Ion Binding	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding
	Biological Process	Phosphatidic Acid Biosynthetic Process Digestion Dephosphorylation	Protein Transport Positive Regulation Of GTPase Activity
Pathways		Synthesis of PA Post-translational modification: synthesis of GPI-anchored proteins Digestion
Drugs
Diseases
GWAS		Hepcidin/ferritin ratio ( 27846281) Refractive error ( 32231278)	Adult body size ( 32376654) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Craniofacial microsomia ( 26853712) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Menarche (age at onset) ( 23667675) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)
Interacting Genes		8 interacting genes: BICD1 HSPB1 IRF5 KRTAP10-3 KRTAP10-8 KRTAP10-9 NOD2 NOTCH2NLA	14 interacting genes: APP ARF1 ARF6 CDC42 GRB7 GUCY1A1 GUCY1B1 RAC1 RHOA RSPH14 SMN1 SRC TK1 ZNF534
Entrez ID		248	116987
HPRD ID		01376	16359
Ensembl ID		ENSG00000163295	ENSG00000157985
Uniprot IDs		A0A024R4A2 P09923	B2RZG9 Q9UPQ3 X5D293
PDB IDs
Enriched GO Terms of Interacting Partners?
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