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TFIP11 and TDP2
Data Source:
BioGRID
(two hybrid)
TFIP11
TDP2
Description
tuftelin interacting protein 11
tyrosyl-DNA phosphodiesterase 2
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Nucleoplasm
Spliceosomal Complex
Nucleolus
Cytoplasm
Nuclear Speck
Extracellular Matrix
U2-type Post-mRNA Release Spliceosomal Complex
Catalytic Step 2 Spliceosome
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Aggresome
Nuclear Body
PML Body
Molecular Function
Nucleic Acid Binding
Protein Binding
Magnesium Ion Binding
Single-stranded DNA Binding
Transcription Corepressor Activity
Nuclease Activity
Protein Binding
Manganese Ion Binding
Tyrosyl-RNA Phosphodiesterase Activity
5'-tyrosyl-DNA Phosphodiesterase Activity
Biological Process
Spliceosomal Complex Disassembly
MRNA Splicing, Via Spliceosome
RNA Processing
Biomineral Tissue Development
Negative Regulation Of Protein-containing Complex Assembly
Protection From Non-homologous End Joining At Telomere
Negative Regulation Of Protein Binding
Negative Regulation Of DNA Ligase Activity
Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Double-strand Break Repair
Cell Surface Receptor Signaling Pathway
Viral Process
Negative Regulation Of Transcription, DNA-templated
Neuron Development
Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
mRNA Splicing - Major Pathway
Nonhomologous End-Joining (NHEJ)
Drugs
Diseases
GWAS
Colorectal or endometrial cancer (
26621817
)
Interacting Genes
232 interacting genes:
AARD
ABI2
ABLIM3
AIMP2
ANKRD11
AP1M1
ARHGEF9
ARMC7
ARMCX1
ARNT2
ATP5PO
ATPAF2
AXIN1
BAZ2B
BCL6
BHLHA9
BMF
BRD1
BYSL
C1orf109
C2CD6
CARD9
CAVIN3
CBX8
CCDC102B
CCDC116
CCDC120
CCDC121
CCDC13
CCDC146
CCDC187
CCDC196
CCDC42
CCDC57
CCDC6
CCDC68
CCDC96
CCHCR1
CCND3
CCNG1
CCNL1
CCP110
CDKN1A
CDR2L
CENPU
CEP57
CEP57L1
CEP95
CFAP206
COQ8A
COX5B
CT55
CWF19L2
DAXX
DDX25
DES
DGCR6
DISC1
DPPA3
DTNB
EAF2
EIF3A
EIF3D
ENOX2
EPM2AIP1
EXOC3L1
EXOC8
EXOSC5
FAM13C
FAM156A
FAM161A
FAM161B
FAM50B
FAM81A
FAM90A1
FANCG
FGA
GADD45GIP1
GAS2L2
GCC1
GCFC2
GEM
GFAP
GNG4
GOLGA1
GOLGA2
GPS2
GRAP2
GSE1
HAUS1
HDAC4
HIP1R
HMG20B
HOOK1
HSF2BP
IKBIP
IL16
IMP3
JRK
KANK2
KANSL1
KAT5
KDM1A
KIF3C
KIF9
KIFC3
KIZ
KRT1
KRT20
KRT6A
KRT6B
KRT6C
KRT8
LATS1
LCA5
LCA5L
LENG1
LIN37
LMNB2
LMO1
LMO2
LMO4
LSM3
LSP1P3
LYSMD1
MAB21L2
MCM7
MDM2
METTL17
MFAP1
MKRN3
MRPL11
MTFR2
MXD3
MYO15B
MYOM1
NDC80
NDE1
NDN
NEK6
NFKBID
NFU1
NSMF
NUP88
ODAD3
OIP5
PBX3
PBX4
PCM1
PDE4DIP
PHF1
PIBF1
PICK1
PKN3
PLK4
POLL
POLR1C
POM121
PPFIA3
PPP1R16A
PPP1R16B
PPP1R18
PRPF31
PSMA4
PSMC5
PSTPIP1
PTCD1
RCOR3
RHNO1
RIN1
RNF6
RRP7A
RUNX1T1
RXRB
S100P
SAP30BP
SCNM1
SFR1
SGF29
SH2D4A
SH3GLB1
SMARCB1
SMARCE1
SNAPIN
SNRPB
SNW1
SNX20
SNX32
SOGA1
SPG21
SSX2IP
STRA8
STRN
SYCE1
TBC1D30
TBRG4
TCAF1
TDP2
TFPT
THAP7
THAP8
TNNT1
TP53
TRAF3IP3
TRAPPC4
TRIM45
TRIML2
TSG101
TSGA10IP
TSHZ2
TSHZ3
TSPYL4
TUFT1
TXLNA
TXN2
UBTFL1
USP2
USP6
USP7
VPS37C
VPS39
WAC
WASHC3
ZC2HC1C
ZFYVE26
ZGPAT
ZMAT2
ZNF417
ZNF572
ZNF587
ZNF777
ZSCAN12
35 interacting genes:
AKAP9
ATP5MC2
ATXN1
BLK
BTBD2
C2orf88
CD40
DLX3
DVL2
EPS8
ETS1
ETS2
FLI1
GOLGA2
JAM2
MAPK6
PSEN1
RAB11A
SKIL
SMAD3
SNX13
SRPK2
SUMO1
SUMO2
SUMO3
TAP1
TFIP11
TNFRSF1B
TNFRSF8
TRAF2
TRAF3
TRAF5
TRAF6
UBE2I
WBP2
Entrez ID
24144
51567
HPRD ID
11628
05771
Ensembl ID
ENSG00000100109
ENSG00000111802
Uniprot IDs
A0A024R1I7
Q9UBB9
A0A384MDM5
O95551
PDB IDs
5INO
5J3P
5J3S
6Q00
6Q01
Enriched GO Terms of Interacting Partners
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