MORC3 and TBX1

Data Source:
BioGRID (unspecified method)

		MORC3	TBX1
Description		MORC family CW-type zinc finger 3	T-box transcription factor 1
Image
GO Annotations	Cellular Component	Nucleoplasm Nuclear Matrix PML Body	Chromatin Nucleus
	Molecular Function	RNA Binding Protein Binding Zinc Ion Binding Methylated Histone Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Protein Phosphorylation Cell Aging Post-embryonic Development Viral Process Peptidyl-serine Phosphorylation Negative Regulation Of Fibroblast Proliferation Protein Stabilization Maintenance Of Protein Location In Nucleus	Angiogenesis Blood Vessel Development Cell Fate Specification Neural Crest Cell Migration Positive Regulation Of Protein Phosphorylation Lymph Vessel Development Positive Regulation Of Mesenchymal Cell Proliferation Heart Morphogenesis Outflow Tract Septum Morphogenesis Outflow Tract Morphogenesis Regulation Of Transcription By RNA Polymerase II Determination Of Left/right Symmetry Pattern Specification Process Mesoderm Development Heart Development Muscle Organ Development Sensory Perception Of Sound Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Anterior/posterior Pattern Specification Vagus Nerve Morphogenesis Epithelial Cell Differentiation Thyroid Gland Development Social Behavior Aorta Morphogenesis Ear Morphogenesis Inner Ear Morphogenesis Outer Ear Morphogenesis Middle Ear Morphogenesis Odontogenesis Of Dentin-containing Tooth Muscle Cell Fate Commitment Positive Regulation Of MAPK Cascade Tongue Morphogenesis Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Retinoic Acid Receptor Signaling Pathway Blood Vessel Morphogenesis Thymus Development Muscle Organ Morphogenesis Embryonic Cranial Skeleton Morphogenesis Embryonic Viscerocranium Morphogenesis Semicircular Canal Morphogenesis Artery Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Parathyroid Gland Development Soft Palate Development Pharyngeal System Development Face Morphogenesis Muscle Tissue Morphogenesis Coronary Artery Morphogenesis Enamel Mineralization Cellular Response To Retinoic Acid Cochlea Morphogenesis Mesenchymal Cell Apoptotic Process Regulation Of Animal Organ Morphogenesis Positive Regulation Of Tongue Muscle Cell Differentiation Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways
Drugs
Diseases			Other well-defined immunodeficiency syndromes, including the following seven diseases: Wiskott-Aldrich syndrome; DiGeorge syndrome; Hyper-IgE syndrome; X-linked lymphoproliferative syndrome; Immunodeficiency, Polyendocrinopathy, Enteropathy, X-linked Syndrome (IPEX); Cartilage-Hair Hypoplasia; Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) Conotruncal heart malformations, including: Double-outlet right ventricle; Persistent truncus arteriosus; Conotruncal anomaly face syndrome Velocardiofacial syndrome
GWAS		Diastolic blood pressure ( 30224653) Height ( 31562340)	Acute kidney injury in critical illness ( 27576016) Adolescent idiopathic scoliosis ( 31417091) Childhood ear infection ( 27182965 28928442) DNA methylation (parent-of-origin) ( 23725790) Interleukin-10 levels ( 22205395) Myringotomy ( 28928442) Prostate cancer ( 25217961) Rheumatoid arthritis ( 30891314) Schizophrenia ( 26198764) Tonsillectomy ( 27182965 28928442)
Interacting Genes		5 interacting genes: ERCC6 KPNA2 RNF216 SUMO2 UBC
Entrez ID		23515	6899
HPRD ID		10316	09069
Ensembl ID		ENSG00000159256	ENSG00000184058
Uniprot IDs		B4DHJ4 Q14149 Q4VBZ9	D9ZGG0 O43435 Q152R5
PDB IDs		4QQ4 5SVI 5SVX 5SVY 6O1E 6O5W	4A04
Enriched GO Terms of Interacting Partners?
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