SEC11A and OAZ2

Data Source:
BioGRID (affinity chromatography technology)

		SEC11A	OAZ2
Description		SEC11 homolog A, signal peptidase complex subunit	ornithine decarboxylase antizyme 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Signal Peptidase Complex Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nucleus Cytoplasm Cytosol
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Signal Peptide Processing	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Negative Regulation Of Catalytic Activity Positive Regulation Of Protein Catabolic Process Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport
Pathways		SRP-dependent cotranslational protein targeting to membrane Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) Synthesis, secretion, and deacylation of Ghrelin	Regulation of ornithine decarboxylase (ODC)
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Response to ketamine in bipolar disorder or major depression (antidepressant effects) ( 30552317) Schizophrenia ( 29483656)	Aluminium levels ( 26025379) Neuroticism ( 29255261)
Interacting Genes		5 interacting genes: ADAM33 BCHE CSNK2B NUPR1 SLC35F6	5 interacting genes: BDKRB1 CDR2 OAZ1 ODC1 SYTL3
Entrez ID		23478	4947
HPRD ID		07503	11966
Ensembl ID		ENSG00000140612	ENSG00000180304
Uniprot IDs		A0A024RC78 H0YKT4 P67812	O95190
PDB IDs
Enriched GO Terms of Interacting Partners?
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